The efficacy and safety of acupoint catgut embedding therapy for depression: a protocol for systematic review and meta-analysis
BackgroundDepression is a common public health problem, characterized by persistent low mood, lack of pleasure and exhaustion. Conventional treatments such as antidepressants and psychotherapy have some limitations, including variable efficacy, adverse side effects and high costs. Acupoint catgut em...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1331780/full |
| _version_ | 1827387710873010176 |
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| author | Yadi Li Jianlong Zhou Zheng Wei Xia He Lizhu Liang Kejimu Sunzi |
| author_facet | Yadi Li Jianlong Zhou Zheng Wei Xia He Lizhu Liang Kejimu Sunzi |
| author_sort | Yadi Li |
| collection | DOAJ |
| description | BackgroundDepression is a common public health problem, characterized by persistent low mood, lack of pleasure and exhaustion. Conventional treatments such as antidepressants and psychotherapy have some limitations, including variable efficacy, adverse side effects and high costs. Acupoint catgut embedding (ACE) therapy, as a subtype of acupuncture, has gained increasing clinical application due to its long-term effects, higher patient compliance, and cost-effectiveness. This study aims to conduct a meta-analysis to evaluate the efficacy and safety of ACE for depression.MethodsElectronic searches will be conducted in 12 databases (both in English and Chinese databases), encompassing from inception to April 2022, without language restrictions. Randomized controlled trials (RCTs) that involve ACE for treating depression will be included. The primary outcome measures will include the response rate, Hamilton Depression Rating Scale (HAMD), Beck Depression Inventory (BDI), and Traditional Chinese Medicine Symptom Scale (TCMSSS). The secondary outcome measure will include Quality of Life scale score (QoL) and the incidence of adverse events. Results will be presented as risk ratios for dichotomous data and mean differences for continuous data. Two reviewers will independently conduct study selection, data extraction, and quality assessment. The methodological quality of eligible studies will be evaluated according to the criteria specified by the Cochrane Handbook for Systematic Reviews of Interventions (Version 5.1.0). Meta-analysis will be performed by RevMan 5.3 software.DiscussionDue to the limitations, a safer, high-efficacy and non-pharmacological intervention with minimal side effects is required for treating depression. ACE has the advantages of longer-lasting effects, improved patient compliance, and reduced treatment costs. This protocol represents a meta-analysis and systematic review, aiming to present the current evidence regarding the efficacy and safety of ACE for depression. It seeks to provide clinicians with a theoretical basis and valuable references for complementary and alternative medicine therapies in their treatment approaches.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/#recordDetails, Identifier CRD42022325966. |
| first_indexed | 2024-03-08T16:07:16Z |
| format | Article |
| id | doaj.art-42f123b5c3d843ffbd5ed621f5bf7a76 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-03-08T16:07:16Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-42f123b5c3d843ffbd5ed621f5bf7a762024-01-08T05:06:09ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402024-01-011410.3389/fpsyt.2023.13317801331780The efficacy and safety of acupoint catgut embedding therapy for depression: a protocol for systematic review and meta-analysisYadi LiJianlong ZhouZheng WeiXia HeLizhu LiangKejimu SunziBackgroundDepression is a common public health problem, characterized by persistent low mood, lack of pleasure and exhaustion. Conventional treatments such as antidepressants and psychotherapy have some limitations, including variable efficacy, adverse side effects and high costs. Acupoint catgut embedding (ACE) therapy, as a subtype of acupuncture, has gained increasing clinical application due to its long-term effects, higher patient compliance, and cost-effectiveness. This study aims to conduct a meta-analysis to evaluate the efficacy and safety of ACE for depression.MethodsElectronic searches will be conducted in 12 databases (both in English and Chinese databases), encompassing from inception to April 2022, without language restrictions. Randomized controlled trials (RCTs) that involve ACE for treating depression will be included. The primary outcome measures will include the response rate, Hamilton Depression Rating Scale (HAMD), Beck Depression Inventory (BDI), and Traditional Chinese Medicine Symptom Scale (TCMSSS). The secondary outcome measure will include Quality of Life scale score (QoL) and the incidence of adverse events. Results will be presented as risk ratios for dichotomous data and mean differences for continuous data. Two reviewers will independently conduct study selection, data extraction, and quality assessment. The methodological quality of eligible studies will be evaluated according to the criteria specified by the Cochrane Handbook for Systematic Reviews of Interventions (Version 5.1.0). Meta-analysis will be performed by RevMan 5.3 software.DiscussionDue to the limitations, a safer, high-efficacy and non-pharmacological intervention with minimal side effects is required for treating depression. ACE has the advantages of longer-lasting effects, improved patient compliance, and reduced treatment costs. This protocol represents a meta-analysis and systematic review, aiming to present the current evidence regarding the efficacy and safety of ACE for depression. It seeks to provide clinicians with a theoretical basis and valuable references for complementary and alternative medicine therapies in their treatment approaches.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/#recordDetails, Identifier CRD42022325966.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1331780/fullacupoint catgut embeddingacupuncturedepressionstudy protocolmeta-analysissystematic review |
| spellingShingle | Yadi Li Jianlong Zhou Zheng Wei Xia He Lizhu Liang Kejimu Sunzi The efficacy and safety of acupoint catgut embedding therapy for depression: a protocol for systematic review and meta-analysis Frontiers in Psychiatry acupoint catgut embedding acupuncture depression study protocol meta-analysis systematic review |
| title | The efficacy and safety of acupoint catgut embedding therapy for depression: a protocol for systematic review and meta-analysis |
| title_full | The efficacy and safety of acupoint catgut embedding therapy for depression: a protocol for systematic review and meta-analysis |
| title_fullStr | The efficacy and safety of acupoint catgut embedding therapy for depression: a protocol for systematic review and meta-analysis |
| title_full_unstemmed | The efficacy and safety of acupoint catgut embedding therapy for depression: a protocol for systematic review and meta-analysis |
| title_short | The efficacy and safety of acupoint catgut embedding therapy for depression: a protocol for systematic review and meta-analysis |
| title_sort | efficacy and safety of acupoint catgut embedding therapy for depression a protocol for systematic review and meta analysis |
| topic | acupoint catgut embedding acupuncture depression study protocol meta-analysis systematic review |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1331780/full |
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