Breast Cancer Subtypes Based on Hypoxia-Related Gene Sets Identify Potential Therapeutic Agents

Breast Cancer Subtypes Based on Hypoxia-Related Gene Sets Identify Potential Therapeutic Agents

Purpose: The hypoxic tumor microenvironment was reported to be involved in different tumorigenesis mechanisms of breast cancer (BC). We aimed to establish a hypoxia-related gene signature to identify a new BC subtype through the clustering analysis and explore potential compounds targeting the BC su...

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Bibliographic Details
Main Authors: Zhenchong Xiong, Weiling Huang, Wenjing Zhong, Jianchang Fu, Jikun Feng, Xi Wang, Feihai Ling
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
breast cancer
hypoxia-related gene sets
clustering analysis
therapeutic agent
subtypes
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.900005/full

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