Epidemiology of continuous renal replacement therapy in Korea: Results from the National Health Insurance Service claims database from 2005 to 2016

Background : Continuous renal replacement therapy (CRRT) is an important treatment modality for severe acute kidney injury. As such, the epidemiology of CRRT in Korea needs further investigation. Methods : We conducted a nationwide, population-based study analyzing the claims data from National Heal...

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Main Authors: Sehoon Park, Soojin Lee, Hyung Ah Jo, Kyungdo Han, Yaerim Kim, Jung Nam An, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Hyeongsu Kim, Dong Ki Kim
Format: Article
Language:English
Published: The Korean Society of Nephrology 2018-06-01
Series:Kidney Research and Clinical Practice
Subjects:
Online Access:https://doi.org/10.23876/j.krcp.2018.37.2.119
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author Sehoon Park
Soojin Lee
Hyung Ah Jo
Kyungdo Han
Yaerim Kim
Jung Nam An
Kwon Wook Joo
Chun Soo Lim
Yon Su Kim
Hyeongsu Kim
Dong Ki Kim
author_facet Sehoon Park
Soojin Lee
Hyung Ah Jo
Kyungdo Han
Yaerim Kim
Jung Nam An
Kwon Wook Joo
Chun Soo Lim
Yon Su Kim
Hyeongsu Kim
Dong Ki Kim
author_sort Sehoon Park
collection DOAJ
description Background : Continuous renal replacement therapy (CRRT) is an important treatment modality for severe acute kidney injury. As such, the epidemiology of CRRT in Korea needs further investigation. Methods : We conducted a nationwide, population-based study analyzing the claims data from National Health Insurance Service of Korea. All index intensive care unit admission cases of CRRT in government-designated tertiary referral hospitals in Korea from 2005 to 2016 were included. Patients with a history of renal replacement therapy or who were under 20 years old were not considered. In addition to baseline and treatment characteristics, patient outcomes, including all-cause mortality and renal survival rates, were investigated. We stratified the study patients according to 3-year time periods and major regions of the nation. Results : We included 37,337 patients who received CRRT in Korea. The overall use of CRRT increased over time, and more than 80% of cases of acute renal replacement therapy were CRRT after 2014. Seoul was the region in which the majority of CRRT (45.0%) was performed. The clinical characteristics of CRRT patients were significantly different among time-intervals and regions. Both all-cause mortality and renal survival rates after CRRT were prominently improved in the recent time periods (P < 0.001). Conclusion : CRRT is a widely used treatment strategy for severe acute kidney injury in Korea. The prognosis of CRRT patients has improved compared to the past. This epidemiological study of CRRT in Korea revealed notable trends with regard to time period and geographic region.
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spelling doaj.art-42f5e45d87814a73b600060c99a2afa42022-12-22T03:49:41ZengThe Korean Society of NephrologyKidney Research and Clinical Practice2211-91322018-06-0137211912910.23876/j.krcp.2018.37.2.119j.krcp.2018.37.2.119Epidemiology of continuous renal replacement therapy in Korea: Results from the National Health Insurance Service claims database from 2005 to 2016Sehoon Park0Soojin Lee1Hyung Ah Jo2Kyungdo Han3Yaerim Kim4Jung Nam An5Kwon Wook Joo6Chun Soo Lim7Yon Su Kim8Hyeongsu Kim9Dong Ki Kim10Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Hospital, Seoul, KoreaDepartment of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, KoreaDepartment of Medical Statistics, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Hospital, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Hospital, Seoul, KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, KoreaDepartment of Preventive Medicine, Konkuk University School of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Hospital, Seoul, KoreaBackground : Continuous renal replacement therapy (CRRT) is an important treatment modality for severe acute kidney injury. As such, the epidemiology of CRRT in Korea needs further investigation. Methods : We conducted a nationwide, population-based study analyzing the claims data from National Health Insurance Service of Korea. All index intensive care unit admission cases of CRRT in government-designated tertiary referral hospitals in Korea from 2005 to 2016 were included. Patients with a history of renal replacement therapy or who were under 20 years old were not considered. In addition to baseline and treatment characteristics, patient outcomes, including all-cause mortality and renal survival rates, were investigated. We stratified the study patients according to 3-year time periods and major regions of the nation. Results : We included 37,337 patients who received CRRT in Korea. The overall use of CRRT increased over time, and more than 80% of cases of acute renal replacement therapy were CRRT after 2014. Seoul was the region in which the majority of CRRT (45.0%) was performed. The clinical characteristics of CRRT patients were significantly different among time-intervals and regions. Both all-cause mortality and renal survival rates after CRRT were prominently improved in the recent time periods (P < 0.001). Conclusion : CRRT is a widely used treatment strategy for severe acute kidney injury in Korea. The prognosis of CRRT patients has improved compared to the past. This epidemiological study of CRRT in Korea revealed notable trends with regard to time period and geographic region.https://doi.org/10.23876/j.krcp.2018.37.2.119Acute kidney injuryContinuous renal replacement therapyCritical careDialysisIntensive care units
spellingShingle Sehoon Park
Soojin Lee
Hyung Ah Jo
Kyungdo Han
Yaerim Kim
Jung Nam An
Kwon Wook Joo
Chun Soo Lim
Yon Su Kim
Hyeongsu Kim
Dong Ki Kim
Epidemiology of continuous renal replacement therapy in Korea: Results from the National Health Insurance Service claims database from 2005 to 2016
Kidney Research and Clinical Practice
Acute kidney injury
Continuous renal replacement therapy
Critical care
Dialysis
Intensive care units
title Epidemiology of continuous renal replacement therapy in Korea: Results from the National Health Insurance Service claims database from 2005 to 2016
title_full Epidemiology of continuous renal replacement therapy in Korea: Results from the National Health Insurance Service claims database from 2005 to 2016
title_fullStr Epidemiology of continuous renal replacement therapy in Korea: Results from the National Health Insurance Service claims database from 2005 to 2016
title_full_unstemmed Epidemiology of continuous renal replacement therapy in Korea: Results from the National Health Insurance Service claims database from 2005 to 2016
title_short Epidemiology of continuous renal replacement therapy in Korea: Results from the National Health Insurance Service claims database from 2005 to 2016
title_sort epidemiology of continuous renal replacement therapy in korea results from the national health insurance service claims database from 2005 to 2016
topic Acute kidney injury
Continuous renal replacement therapy
Critical care
Dialysis
Intensive care units
url https://doi.org/10.23876/j.krcp.2018.37.2.119
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