Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor tics
This overview on Volkameria inermis (Lamiaceae) is the first in updating information on the chemical constituents and pharmacological properties of the species, notably on its unique ability in ameliorating motor tics. The information was procured from Google, Google Scholar, PubMed, PubMed Central,...
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| Format: | Article |
| Language: | English |
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Shahrekord University of Medical Sciences
2023-04-01
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| Series: | Journal of HerbMed Pharmacology |
| Subjects: | |
| Online Access: | http://herbmedpharmacol.com/PDF/jhp-12-176.pdf |
| _version_ | 1797839597941555200 |
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| author | Eric Wei Chiang Chan Siu Kuin Wong Hung Tuck Chan |
| author_facet | Eric Wei Chiang Chan Siu Kuin Wong Hung Tuck Chan |
| author_sort | Eric Wei Chiang Chan |
| collection | DOAJ |
| description | This overview on Volkameria inermis (Lamiaceae) is the first in updating information on the chemical constituents and pharmacological properties of the species, notably on its unique ability in ameliorating motor tics. The information was procured from Google, Google Scholar, PubMed, PubMed Central, Science Direct, J-Stage, and PubChem. Previously named Clerodendrum inerme (Verbenaceae), V. inermis is a scrambling or scandent coastal shrub in the tropics and sub-tropics. From different parts of the plant, compounds such as flavonoids, diterpenes/diterpenoids, sterols, triterpenes/triterpenoids, iridoid glycosides, phenolic glycosides, phenylethanoid glycosides (PEGs), phenylpropanoid glycosides (PPGs), chalcones, and sesquiterpenes have been reported. Major pharmacological properties of V. inermis include anti-cancer, anti-inflammatory, antioxidant, hepatoprotective, analgesic, and antibacterial activities. Other properties include anti-tyrosinase, antifungal, neuroprotective, hypotensive, hypoglycemic, amyloid-β aggregation, wound healing, antipyretic, and larvicidal activities. A unique pharmacological property of V. inermis leaf extract, discovered by scientists from Taiwan, is the amelioration of motor tic disorders, a spectrum of Tourette syndrome. This property included a case report, three in vivo studies, and one patent. Areas of further research of V. inermis are suggested. |
| first_indexed | 2024-04-09T16:00:36Z |
| format | Article |
| id | doaj.art-42f8b2a86d7249c3b4e48f4482e89702 |
| institution | Directory Open Access Journal |
| issn | 2345-5004 |
| language | English |
| last_indexed | 2024-04-09T16:00:36Z |
| publishDate | 2023-04-01 |
| publisher | Shahrekord University of Medical Sciences |
| record_format | Article |
| series | Journal of HerbMed Pharmacology |
| spelling | doaj.art-42f8b2a86d7249c3b4e48f4482e897022023-04-25T12:41:55ZengShahrekord University of Medical SciencesJournal of HerbMed Pharmacology2345-50042023-04-0112217618610.34172/jhp.2023.18jhp-44756Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor ticsEric Wei Chiang Chan0Siu Kuin Wong1Hung Tuck Chan2Faculty of Applied Sciences, UCSI University, 56000 Cheras, Kuala Lumpur, MalaysiaSchool of Foundation Studies, Xiamen University Malaysia, Bandar Sunsuria, 43900 Sepang, Selangor, MalaysiaSecretariat of International Society for Mangrove Ecosystems (ISME), Faculty of Agriculture, University of the Ryukyus, Okinawa 903-0129, JapanThis overview on Volkameria inermis (Lamiaceae) is the first in updating information on the chemical constituents and pharmacological properties of the species, notably on its unique ability in ameliorating motor tics. The information was procured from Google, Google Scholar, PubMed, PubMed Central, Science Direct, J-Stage, and PubChem. Previously named Clerodendrum inerme (Verbenaceae), V. inermis is a scrambling or scandent coastal shrub in the tropics and sub-tropics. From different parts of the plant, compounds such as flavonoids, diterpenes/diterpenoids, sterols, triterpenes/triterpenoids, iridoid glycosides, phenolic glycosides, phenylethanoid glycosides (PEGs), phenylpropanoid glycosides (PPGs), chalcones, and sesquiterpenes have been reported. Major pharmacological properties of V. inermis include anti-cancer, anti-inflammatory, antioxidant, hepatoprotective, analgesic, and antibacterial activities. Other properties include anti-tyrosinase, antifungal, neuroprotective, hypotensive, hypoglycemic, amyloid-β aggregation, wound healing, antipyretic, and larvicidal activities. A unique pharmacological property of V. inermis leaf extract, discovered by scientists from Taiwan, is the amelioration of motor tic disorders, a spectrum of Tourette syndrome. This property included a case report, three in vivo studies, and one patent. Areas of further research of V. inermis are suggested.http://herbmedpharmacol.com/PDF/jhp-12-176.pdfclerodendrum inermeflavonoidstourette syndromemotor tics |
| spellingShingle | Eric Wei Chiang Chan Siu Kuin Wong Hung Tuck Chan Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor tics Journal of HerbMed Pharmacology clerodendrum inerme flavonoids tourette syndrome motor tics |
| title | Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor tics |
| title_full | Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor tics |
| title_fullStr | Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor tics |
| title_full_unstemmed | Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor tics |
| title_short | Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor tics |
| title_sort | volkameria inermis an overview of its chemical constituents and pharmacological properties notably the amelioration of motor tics |
| topic | clerodendrum inerme flavonoids tourette syndrome motor tics |
| url | http://herbmedpharmacol.com/PDF/jhp-12-176.pdf |
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