Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis

Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis

Macrophages are the preeminent phagocytic cells which control multiple infections. Tuberculosis a leading cause of death in mankind and the causative organism Mycobacterium tuberculosis (MTB) infects and persists in macrophages. Macrophages use reactive oxygen and nitrogen species (ROS/RNS) and auto...

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Bibliographic Details
Main Authors: Kangling Zhang, Mark L. Sowers, Ellie I. Cherryhomes, Vipul K. Singh, Abhishek Mishra, Blanca I. Restrepo, Arshad Khan, Chinnaswamy Jagannath
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
human macrophages
autophagy
glycolysis
metabolism
histone modifications
SIRTUIN
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1121495/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1121495/full

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