Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis

Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis

Macrophages are the preeminent phagocytic cells which control multiple infections. Tuberculosis a leading cause of death in mankind and the causative organism Mycobacterium tuberculosis (MTB) infects and persists in macrophages. Macrophages use reactive oxygen and nitrogen species (ROS/RNS) and auto...

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Bibliographic Details
Main Authors:	Kangling Zhang, Mark L. Sowers, Ellie I. Cherryhomes, Vipul K. Singh, Abhishek Mishra, Blanca I. Restrepo, Arshad Khan, Chinnaswamy Jagannath
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Immunology
Subjects:	human macrophages autophagy glycolysis metabolism histone modifications SIRTUIN
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1121495/full

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