Immune activation of the p75 neurotrophin receptor: implications in neuroinflammation

Immune activation of the p75 neurotrophin receptor: implications in neuroinflammation

Despite structural similarity with other tumor necrosis factor receptor superfamily (TNFRSF) members, the p75 neurotrophin receptor (p75NTR, TNFR16) mediates pleiotropic biological functions not shared with other TNFRs. The high level of p75NTR expression in the nervous system instead of immune cell...

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Bibliographic Details
Main Authors: Victor Danelon, Sarah C. Garret-Thomson, Steven C. Almo, Francis S. Lee, Barbara L. Hempstead
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
p75NTR
neurotrophin
B7-1
CD80
TNF receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1305574/full

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