The interaction effects between TLR4 and MMP9 gene polymorphisms contribute to aortic aneurysm risk in a Chinese Han population

Abstract Background A cross-talk between Toll-like receptor 4 (TLR4) and matrix metalloproteinase 9 (MMP9) plays a vital role in aortic pathophysiology. The objective of this study was to evaluate the interactions between TLR4 and MMP9 polymorphisms in the risk of aortic aneurysm (AA) and its subtyp...

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Bibliographic Details
Main Authors: Tan Li, Xu Zhang, Liang Sang, Xin-tong Li, Hai-yang Sun, Jun Yang, Yuan Yuan
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12872-019-1049-8