Anaerobic expression of the gadE-mdtEF multidrug efflux operon is primarily regulated by the two-component system ArcBA through antagonizing the H-NS mediated repression

Anaerobic expression of the gadE-mdtEF multidrug efflux operon is primarily regulated by the two-component system ArcBA through antagonizing the H-NS mediated repression

The gadE-mdtEF operon encodes a central acid resistance regulator GadE and two multidrug efflux proteins MdtEF. Although transcriptional regulation of gadE in the context of acid resistance under the aerobic growth environment of E. coli has been extensively studied, regulation of the operon under t...

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Bibliographic Details
Main Authors: Ziqing eDeng, Yue eShan, Qing ePan, Xiang eGao, Aixin eYan
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Microbiology
Subjects:
Acid Resistance
Multidrug efflux pump
Anaerobic adaptation
H-NS
ArcBA two-component system
Antagonization
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00194/full

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