Clinical characteristics of acute drug-induced dystonia in pediatric patients

Objecstonia is a movement disorder in which muscles contract uncontrollably. Acute drug-induced dystonia (DID) can be diagnosed through detailed history taking and physical examination. This study aimed to identify the clinical characteristics of DID in children, which could help emergency physician...

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Main Authors: Hyun Woong Park, Jae Ryung Kwak, Ji Sook Lee
Format: Article
Language:English
Published: The Korean Society of Emergency Medicine 2017-09-01
Series:Clinical and Experimental Emergency Medicine
Subjects:
Online Access:http://www.ceemjournal.org/upload/pdf/ceem-16-181.pdf
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author Hyun Woong Park
Jae Ryung Kwak
Ji Sook Lee
author_facet Hyun Woong Park
Jae Ryung Kwak
Ji Sook Lee
author_sort Hyun Woong Park
collection DOAJ
description Objecstonia is a movement disorder in which muscles contract uncontrollably. Acute drug-induced dystonia (DID) can be diagnosed through detailed history taking and physical examination. This study aimed to identify the clinical characteristics of DID in children, which could help emergency physicians diagnose these conditions more efficiently. Methods We reviewed medical rtive Dyecords of children aged below 18 years diagnosed with drug-related dystonia after discharge from the emergency department over 10 years. We collected the patients’ age, sex, suspected causative drugs, initial diagnosis of the prescribing physician, duration of drug-taking, diagnostic evaluations, treatment methods, and prognosis. Results Seventy-nine patients were enrolled. The mean age was 11.3±4.9 years (range, 4.0 months to 18.0 years), and 41 patients (51.9%) were boys. The most common cause of DID was gastrointestinal medications in 45 patients (57.0%), followed by antipsychotics in 23 patients (29.1%). Eleven (24.4%) out of 45 patients with DID due to gastrointestinal medications had the initial diagnosis of upper respiratory infection, and seven (30.4%) out of 23 patients with DID due to antipsychotics had the initial diagnosis of non-psychotic diseases. Younger children received more diagnostic procedures and were more frequently admitted. A benzodiazepine (67.1%) was the most common single drug for treatment. Conclusion Physicians should not only acknowledge DID in order to reduce unnecessary workup and admission, but also know that antiemetics and antipsychotics are common causes of DID. Therefore, physicians should try to avoid multidrug prescriptions in children.
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spelling doaj.art-4311593ca5524b3f85821a4bc77c66192023-02-24T00:01:38ZengThe Korean Society of Emergency MedicineClinical and Experimental Emergency Medicine2383-46252017-09-014313313710.15441/ceem.16.181144Clinical characteristics of acute drug-induced dystonia in pediatric patientsHyun Woong ParkJae Ryung KwakJi Sook LeeObjecstonia is a movement disorder in which muscles contract uncontrollably. Acute drug-induced dystonia (DID) can be diagnosed through detailed history taking and physical examination. This study aimed to identify the clinical characteristics of DID in children, which could help emergency physicians diagnose these conditions more efficiently. Methods We reviewed medical rtive Dyecords of children aged below 18 years diagnosed with drug-related dystonia after discharge from the emergency department over 10 years. We collected the patients’ age, sex, suspected causative drugs, initial diagnosis of the prescribing physician, duration of drug-taking, diagnostic evaluations, treatment methods, and prognosis. Results Seventy-nine patients were enrolled. The mean age was 11.3±4.9 years (range, 4.0 months to 18.0 years), and 41 patients (51.9%) were boys. The most common cause of DID was gastrointestinal medications in 45 patients (57.0%), followed by antipsychotics in 23 patients (29.1%). Eleven (24.4%) out of 45 patients with DID due to gastrointestinal medications had the initial diagnosis of upper respiratory infection, and seven (30.4%) out of 23 patients with DID due to antipsychotics had the initial diagnosis of non-psychotic diseases. Younger children received more diagnostic procedures and were more frequently admitted. A benzodiazepine (67.1%) was the most common single drug for treatment. Conclusion Physicians should not only acknowledge DID in order to reduce unnecessary workup and admission, but also know that antiemetics and antipsychotics are common causes of DID. Therefore, physicians should try to avoid multidrug prescriptions in children.http://www.ceemjournal.org/upload/pdf/ceem-16-181.pdfpharmaceutical preparationsdystoniachild
spellingShingle Hyun Woong Park
Jae Ryung Kwak
Ji Sook Lee
Clinical characteristics of acute drug-induced dystonia in pediatric patients
Clinical and Experimental Emergency Medicine
pharmaceutical preparations
dystonia
child
title Clinical characteristics of acute drug-induced dystonia in pediatric patients
title_full Clinical characteristics of acute drug-induced dystonia in pediatric patients
title_fullStr Clinical characteristics of acute drug-induced dystonia in pediatric patients
title_full_unstemmed Clinical characteristics of acute drug-induced dystonia in pediatric patients
title_short Clinical characteristics of acute drug-induced dystonia in pediatric patients
title_sort clinical characteristics of acute drug induced dystonia in pediatric patients
topic pharmaceutical preparations
dystonia
child
url http://www.ceemjournal.org/upload/pdf/ceem-16-181.pdf
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