Clinical characteristics of acute drug-induced dystonia in pediatric patients
Objecstonia is a movement disorder in which muscles contract uncontrollably. Acute drug-induced dystonia (DID) can be diagnosed through detailed history taking and physical examination. This study aimed to identify the clinical characteristics of DID in children, which could help emergency physician...
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Format: | Article |
Language: | English |
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The Korean Society of Emergency Medicine
2017-09-01
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Series: | Clinical and Experimental Emergency Medicine |
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Online Access: | http://www.ceemjournal.org/upload/pdf/ceem-16-181.pdf |
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author | Hyun Woong Park Jae Ryung Kwak Ji Sook Lee |
author_facet | Hyun Woong Park Jae Ryung Kwak Ji Sook Lee |
author_sort | Hyun Woong Park |
collection | DOAJ |
description | Objecstonia is a movement disorder in which muscles contract uncontrollably. Acute drug-induced dystonia (DID) can be diagnosed through detailed history taking and physical examination. This study aimed to identify the clinical characteristics of DID in children, which could help emergency physicians diagnose these conditions more efficiently. Methods We reviewed medical rtive Dyecords of children aged below 18 years diagnosed with drug-related dystonia after discharge from the emergency department over 10 years. We collected the patients’ age, sex, suspected causative drugs, initial diagnosis of the prescribing physician, duration of drug-taking, diagnostic evaluations, treatment methods, and prognosis. Results Seventy-nine patients were enrolled. The mean age was 11.3±4.9 years (range, 4.0 months to 18.0 years), and 41 patients (51.9%) were boys. The most common cause of DID was gastrointestinal medications in 45 patients (57.0%), followed by antipsychotics in 23 patients (29.1%). Eleven (24.4%) out of 45 patients with DID due to gastrointestinal medications had the initial diagnosis of upper respiratory infection, and seven (30.4%) out of 23 patients with DID due to antipsychotics had the initial diagnosis of non-psychotic diseases. Younger children received more diagnostic procedures and were more frequently admitted. A benzodiazepine (67.1%) was the most common single drug for treatment. Conclusion Physicians should not only acknowledge DID in order to reduce unnecessary workup and admission, but also know that antiemetics and antipsychotics are common causes of DID. Therefore, physicians should try to avoid multidrug prescriptions in children. |
first_indexed | 2024-04-10T07:29:37Z |
format | Article |
id | doaj.art-4311593ca5524b3f85821a4bc77c6619 |
institution | Directory Open Access Journal |
issn | 2383-4625 |
language | English |
last_indexed | 2024-04-10T07:29:37Z |
publishDate | 2017-09-01 |
publisher | The Korean Society of Emergency Medicine |
record_format | Article |
series | Clinical and Experimental Emergency Medicine |
spelling | doaj.art-4311593ca5524b3f85821a4bc77c66192023-02-24T00:01:38ZengThe Korean Society of Emergency MedicineClinical and Experimental Emergency Medicine2383-46252017-09-014313313710.15441/ceem.16.181144Clinical characteristics of acute drug-induced dystonia in pediatric patientsHyun Woong ParkJae Ryung KwakJi Sook LeeObjecstonia is a movement disorder in which muscles contract uncontrollably. Acute drug-induced dystonia (DID) can be diagnosed through detailed history taking and physical examination. This study aimed to identify the clinical characteristics of DID in children, which could help emergency physicians diagnose these conditions more efficiently. Methods We reviewed medical rtive Dyecords of children aged below 18 years diagnosed with drug-related dystonia after discharge from the emergency department over 10 years. We collected the patients’ age, sex, suspected causative drugs, initial diagnosis of the prescribing physician, duration of drug-taking, diagnostic evaluations, treatment methods, and prognosis. Results Seventy-nine patients were enrolled. The mean age was 11.3±4.9 years (range, 4.0 months to 18.0 years), and 41 patients (51.9%) were boys. The most common cause of DID was gastrointestinal medications in 45 patients (57.0%), followed by antipsychotics in 23 patients (29.1%). Eleven (24.4%) out of 45 patients with DID due to gastrointestinal medications had the initial diagnosis of upper respiratory infection, and seven (30.4%) out of 23 patients with DID due to antipsychotics had the initial diagnosis of non-psychotic diseases. Younger children received more diagnostic procedures and were more frequently admitted. A benzodiazepine (67.1%) was the most common single drug for treatment. Conclusion Physicians should not only acknowledge DID in order to reduce unnecessary workup and admission, but also know that antiemetics and antipsychotics are common causes of DID. Therefore, physicians should try to avoid multidrug prescriptions in children.http://www.ceemjournal.org/upload/pdf/ceem-16-181.pdfpharmaceutical preparationsdystoniachild |
spellingShingle | Hyun Woong Park Jae Ryung Kwak Ji Sook Lee Clinical characteristics of acute drug-induced dystonia in pediatric patients Clinical and Experimental Emergency Medicine pharmaceutical preparations dystonia child |
title | Clinical characteristics of acute drug-induced dystonia in pediatric patients |
title_full | Clinical characteristics of acute drug-induced dystonia in pediatric patients |
title_fullStr | Clinical characteristics of acute drug-induced dystonia in pediatric patients |
title_full_unstemmed | Clinical characteristics of acute drug-induced dystonia in pediatric patients |
title_short | Clinical characteristics of acute drug-induced dystonia in pediatric patients |
title_sort | clinical characteristics of acute drug induced dystonia in pediatric patients |
topic | pharmaceutical preparations dystonia child |
url | http://www.ceemjournal.org/upload/pdf/ceem-16-181.pdf |
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