Exosomes mediated fibrogenesis in dilated cardiomyopathy through a MicroRNA pathway

Exosomes mediated fibrogenesis in dilated cardiomyopathy through a MicroRNA pathway

Summary: Cardiac fibrosis is a hallmark in late-stage familial dilated cardiomyopathy (DCM) patients, although the underlying mechanism remains elusive. Cardiac exosomes (Exos) have been reported relating to fibrosis in ischemic cardiomyopathy. Thus, we investigated whether Exos secreted from the fa...

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Bibliographic Details
Main Authors: Xuebin Fu, Rachana Mishra, Ling Chen, Mir Yasir Arfat, Sudhish Sharma, Tami Kingsbury, Muthukumar Gunasekaran, Progyaparamita Saha, Charles Hong, Peixin Yang, Deqiang Li, Sunjay Kaushal
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Fibrosis
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223000408

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