Case Report: Functional and Symptomatic Improvement With Cariprazine in Various Psychiatric Patients: A Case Series
Cariprazine is a third-generation antipsychotic medication approved for the treatment of schizophrenia and bipolar disorder, with unique pharmacodynamic and pharmacokinetic properties. In this case series, the functional and symptomatic improvement of three patients who had been diagnosed with diffe...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.878889/full |
| _version_ | 1818491807643729920 |
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| author | Tommaso Vannucchi Costanza Taddeucci Lorenzo Tatini |
| author_facet | Tommaso Vannucchi Costanza Taddeucci Lorenzo Tatini |
| author_sort | Tommaso Vannucchi |
| collection | DOAJ |
| description | Cariprazine is a third-generation antipsychotic medication approved for the treatment of schizophrenia and bipolar disorder, with unique pharmacodynamic and pharmacokinetic properties. In this case series, the functional and symptomatic improvement of three patients who had been diagnosed with different psychiatric disorders and who exhibited various symptoms from psychotic to mood symptoms is described. The first case is about a young male patient with bipolar disorder and cocaine abuse who managed to become abstinent from cariprazine. The second and third cases describe patients with psychosis suffering from positive, cognitive and mood symptoms who were non-adherent to previous medication. In both cases, cariprazine was well-tolerated and effective in alleviating symptoms, thus improving their everyday functioning as well. In the discussion, the associations between symptom domains and the receptor profile of cariprazine are also highlighted, providing an explanation of the observed effects. It is concluded that cariprazine is a good treatment option for patients with symptoms of psychosis and addiction; is well-tolerated without the induction of side effects such as weight gain or sedation; and is appropriate for patients who have problems with adherence. |
| first_indexed | 2024-12-10T17:35:32Z |
| format | Article |
| id | doaj.art-4312c4a1b0014ced8b8a53db99928f73 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-10T17:35:32Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-4312c4a1b0014ced8b8a53db99928f732022-12-22T01:39:32ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-08-011310.3389/fpsyt.2022.878889878889Case Report: Functional and Symptomatic Improvement With Cariprazine in Various Psychiatric Patients: A Case SeriesTommaso VannucchiCostanza TaddeucciLorenzo TatiniCariprazine is a third-generation antipsychotic medication approved for the treatment of schizophrenia and bipolar disorder, with unique pharmacodynamic and pharmacokinetic properties. In this case series, the functional and symptomatic improvement of three patients who had been diagnosed with different psychiatric disorders and who exhibited various symptoms from psychotic to mood symptoms is described. The first case is about a young male patient with bipolar disorder and cocaine abuse who managed to become abstinent from cariprazine. The second and third cases describe patients with psychosis suffering from positive, cognitive and mood symptoms who were non-adherent to previous medication. In both cases, cariprazine was well-tolerated and effective in alleviating symptoms, thus improving their everyday functioning as well. In the discussion, the associations between symptom domains and the receptor profile of cariprazine are also highlighted, providing an explanation of the observed effects. It is concluded that cariprazine is a good treatment option for patients with symptoms of psychosis and addiction; is well-tolerated without the induction of side effects such as weight gain or sedation; and is appropriate for patients who have problems with adherence.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.878889/fullpartial agonistcariprazineschizophreniadrug abusebipolar disordercocaine-seeking relapse |
| spellingShingle | Tommaso Vannucchi Costanza Taddeucci Lorenzo Tatini Case Report: Functional and Symptomatic Improvement With Cariprazine in Various Psychiatric Patients: A Case Series Frontiers in Psychiatry partial agonist cariprazine schizophrenia drug abuse bipolar disorder cocaine-seeking relapse |
| title | Case Report: Functional and Symptomatic Improvement With Cariprazine in Various Psychiatric Patients: A Case Series |
| title_full | Case Report: Functional and Symptomatic Improvement With Cariprazine in Various Psychiatric Patients: A Case Series |
| title_fullStr | Case Report: Functional and Symptomatic Improvement With Cariprazine in Various Psychiatric Patients: A Case Series |
| title_full_unstemmed | Case Report: Functional and Symptomatic Improvement With Cariprazine in Various Psychiatric Patients: A Case Series |
| title_short | Case Report: Functional and Symptomatic Improvement With Cariprazine in Various Psychiatric Patients: A Case Series |
| title_sort | case report functional and symptomatic improvement with cariprazine in various psychiatric patients a case series |
| topic | partial agonist cariprazine schizophrenia drug abuse bipolar disorder cocaine-seeking relapse |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.878889/full |
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