Depression and Anxiety after Acute Myocardial Infarction Treated by Primary PCI.

AIMS:The main objective of the study was to find out prevalence of depression and anxiety symptoms in the population of patients with AMI with ST-segment elevation (STEMI), treated with primary PCI (pPCI). Secondary target indicators included the incidence of sleep disorders and loss of interest in...

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Main Authors: Petr Kala, Nela Hudakova, Michal Jurajda, Tomas Kasparek, Libor Ustohal, Jiri Parenica, Marek Sebo, Maria Holicka, Jan Kanovsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4830576?pdf=render
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author Petr Kala
Nela Hudakova
Michal Jurajda
Tomas Kasparek
Libor Ustohal
Jiri Parenica
Marek Sebo
Maria Holicka
Jan Kanovsky
author_facet Petr Kala
Nela Hudakova
Michal Jurajda
Tomas Kasparek
Libor Ustohal
Jiri Parenica
Marek Sebo
Maria Holicka
Jan Kanovsky
author_sort Petr Kala
collection DOAJ
description AIMS:The main objective of the study was to find out prevalence of depression and anxiety symptoms in the population of patients with AMI with ST-segment elevation (STEMI), treated with primary PCI (pPCI). Secondary target indicators included the incidence of sleep disorders and loss of interest in sex. METHODS AND RESULTS:The project enrolled 79 consecutive patients with the first AMI, aged <80 years (median 61 years, 21.5% of women) with a follow-up period of 12 months. Symptoms of depression or anxiety were measured using the Beck Depression Inventory II tests (BDI-II, cut-off value ≥14) and Self-Rating Anxiety Scale (SAS, cut-off ≥ 45) within 24 hours of pPCI, before the discharge, and in 3, 6 and 12 months). Results with the value p<0.05 were considered as statistically significant. The BDI-II positivity was highest within 24 hours after pPCI (21.5%) with a significant decline prior to the discharge (9.2%), but with a gradual increase in 3, 6 and 12 months (10.4%; 15.4%; 13.8% respectively). The incidence of anxiety showed a relatively similar trend: 8.9% after pPCI, and 4.5%, 10.8% and 6.2% in further follow-up. CONCLUSIONS:Patients with STEMI treated by primary PCI have relatively low overall prevalence of symptoms of depression and anxiety. A significant decrease in mental stress was observed before discharge from the hospital, but in a period of one year after pPCI, prevalence of both symptoms was gradually increasing, which should be given medical attention.
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spelling doaj.art-431a8137f9e94de6adcac6dc04f4cc1e2022-12-22T03:58:11ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01114e015236710.1371/journal.pone.0152367Depression and Anxiety after Acute Myocardial Infarction Treated by Primary PCI.Petr KalaNela HudakovaMichal JurajdaTomas KasparekLibor UstohalJiri ParenicaMarek SeboMaria HolickaJan KanovskyAIMS:The main objective of the study was to find out prevalence of depression and anxiety symptoms in the population of patients with AMI with ST-segment elevation (STEMI), treated with primary PCI (pPCI). Secondary target indicators included the incidence of sleep disorders and loss of interest in sex. METHODS AND RESULTS:The project enrolled 79 consecutive patients with the first AMI, aged <80 years (median 61 years, 21.5% of women) with a follow-up period of 12 months. Symptoms of depression or anxiety were measured using the Beck Depression Inventory II tests (BDI-II, cut-off value ≥14) and Self-Rating Anxiety Scale (SAS, cut-off ≥ 45) within 24 hours of pPCI, before the discharge, and in 3, 6 and 12 months). Results with the value p<0.05 were considered as statistically significant. The BDI-II positivity was highest within 24 hours after pPCI (21.5%) with a significant decline prior to the discharge (9.2%), but with a gradual increase in 3, 6 and 12 months (10.4%; 15.4%; 13.8% respectively). The incidence of anxiety showed a relatively similar trend: 8.9% after pPCI, and 4.5%, 10.8% and 6.2% in further follow-up. CONCLUSIONS:Patients with STEMI treated by primary PCI have relatively low overall prevalence of symptoms of depression and anxiety. A significant decrease in mental stress was observed before discharge from the hospital, but in a period of one year after pPCI, prevalence of both symptoms was gradually increasing, which should be given medical attention.http://europepmc.org/articles/PMC4830576?pdf=render
spellingShingle Petr Kala
Nela Hudakova
Michal Jurajda
Tomas Kasparek
Libor Ustohal
Jiri Parenica
Marek Sebo
Maria Holicka
Jan Kanovsky
Depression and Anxiety after Acute Myocardial Infarction Treated by Primary PCI.
PLoS ONE
title Depression and Anxiety after Acute Myocardial Infarction Treated by Primary PCI.
title_full Depression and Anxiety after Acute Myocardial Infarction Treated by Primary PCI.
title_fullStr Depression and Anxiety after Acute Myocardial Infarction Treated by Primary PCI.
title_full_unstemmed Depression and Anxiety after Acute Myocardial Infarction Treated by Primary PCI.
title_short Depression and Anxiety after Acute Myocardial Infarction Treated by Primary PCI.
title_sort depression and anxiety after acute myocardial infarction treated by primary pci
url http://europepmc.org/articles/PMC4830576?pdf=render
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