Effects of Mdivi-1 on Neural Mitochondrial Dysfunction and Mitochondria-Mediated Apoptosis in Ischemia-Reperfusion Injury After Stroke: A Systematic Review of Preclinical Studies

Effects of Mdivi-1 on Neural Mitochondrial Dysfunction and Mitochondria-Mediated Apoptosis in Ischemia-Reperfusion Injury After Stroke: A Systematic Review of Preclinical Studies

This systematic review sought to determine the effects of Mitochondrial division inhibitor-1 (Mdivi-1) on neural mitochondrial dysfunction and neural mitochondria-mediated apoptosis in ischemia/reperfusion (I/R) injury after ischemic stroke. Pubmed, Web of Science, and EMBASE databases were searched...

Full description

Bibliographic Details
Main Authors:	Nguyen Thanh Nhu, Qing Li, Yijie Liu, Jian Xu, Shu-Yun Xiao, Shin-Da Lee
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-12-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	Mdivi-1 mitochondrial function apoptosis ischemia-reperfusion injury stroke
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2021.778569/full

Similar Items

Protective effect of mdivi-1 on heart of mice after acute myocardial ischemia
by: LI Qinghui, et al.
Published: (2021-07-01)

Pleiotropic effects of mdivi-1 in altering mitochondrial dynamics, respiration, and autophagy in cardiomyocytes
by: Richa Aishwarya, et al.
Published: (2020-09-01)

Protective effects of mitochondrial fission inhibitor, Mdivi-1, on traumatic shock rats at high altitude
by: WU Yue, et al.
Published: (2022-10-01)

Therapeutic Effect of Mitochondrial Division Inhibitor-1 (Mdivi-1) on Hyperglycemia-Exacerbated Early and Delayed Brain Injuries after Experimental Subarachnoid Hemorrhage
by: Chia-Li Chung, et al.
Published: (2022-06-01)

Melatonin Protects Against Mdivi-1-Induced Abnormal Spindle Assembly and Mitochondrial Superoxide Production During Porcine Oocyte Maturation
by: Seul-Gi Yang, et al.
Published: (2021-07-01)

Mitochondrial division inhibitor Mdivi-1 protects intestinal barrier function in septic rats
by: TANG Chunqiong, et al.
Published: (2024-03-01)

Inhibition of DRP1-dependent mitochondrial fission by Mdivi-1 alleviates atherosclerosis through the modulation of M1 polarization
by: Ze-da-zhong Su, et al.
Published: (2023-06-01)

DRP1 Inhibition Rescues Mitochondrial Integrity and Excessive Apoptosis in CS-A Disease Cell Models
by: Barbara Pascucci, et al.
Published: (2021-07-01)

Mitochondrial Division Inhibitor 1 (mdivi-1) Protects Neurons against Excitotoxicity through the Modulation of Mitochondrial Function and Intracellular Ca2+ Signaling
by: Asier Ruiz, et al.
Published: (2018-01-01)

The role of mitochondrial dynamics in cerebral ischemia-reperfusion injury
by: Jie Huang, et al.
Published: (2023-06-01)

Perspectives on mitochondrial relevance in cardiac ischemia/reperfusion injury
by: Gaia Pedriali, et al.
Published: (2022-12-01)

DRP1 Regulation as a Potential Target in Hypoxia-Induced Cerebral Pathology
by: Evgenia N. Fedorova, et al.
Published: (2023-12-01)

Mdivi-1 attenuates oxidative stress and exerts vascular protection in ischemic/hypoxic injury by a mechanism independent of Drp1 GTPase activity
by: Chenyang Duan, et al.
Published: (2020-10-01)

Metformin and Sildenafil Attenuate Inflammation and Suppress Apoptosis After Ischemia/Reperfusion Injuries in Rat Urinary Bladder
by: Jong Mok Park, et al.
Published: (2021-12-01)

Shaping of Hepatic Ischemia/Reperfusion Events: The Crucial Role of Mitochondria
by: João S. Teodoro, et al.
Published: (2022-02-01)

The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury
by: Andrey V. Kuznetsov, et al.
Published: (2019-10-01)

Mitochondrial quality control in hepatic ischemia-reperfusion injury
by: LiuSong Wang, et al.
Published: (2023-07-01)

The effect of time on apoptosis changes following ischemia-reperfusion in isolated heart of rats
by: Mehrdad Hashemi, et al.
Published: (2018-02-01)

Serum Metabolomics Reveals Distinct Profiles during Ischemia and Reperfusion in a Porcine Model of Myocardial Ischemia–Reperfusion
by: Eric Goetzman, et al.
Published: (2022-06-01)

Comparative Transcriptomics of <i>Chilodonella hexasticha</i> and <i>C. uncinata</i> Provide New Insights into Adaptations to a Parasitic Lifestyle and Mdivi-1 as a Potential Agent for Chilodonellosis Control
by: Xialian Bu, et al.
Published: (2023-08-01)

Vitamin D Attenuates Ischemia/Reperfusion-Induced Cardiac Injury by Reducing Mitochondrial Fission and Mitophagy
by: Tzu-Lin Lee, et al.
Published: (2020-12-01)

Hydrogen sulfide-mediated cardioprotection against ischemia reperfusion is linked to KATP channel for mitochondrial preservation but not for its distinct preference on interfibrillar mitochondria
by: Priyadharshini Chandrasekaran, et al.
Published: (2019-06-01)

Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction
by: Jia Guo, et al.
Published: (2022-10-01)

Panax Quinquefolium Saponin Attenuates Cardiomyocyte Apoptosis and Opening of the Mitochondrial Permeability Transition Pore in a Rat Model of Ischemia/Reperfusion
by: Dong Li, et al.
Published: (2014-10-01)

ER–Mitochondria Microdomains in Cardiac Ischemia–Reperfusion Injury: A Fresh Perspective
by: Hao Zhou, et al.
Published: (2018-06-01)

Activation of Autophagic Flux Maintains Mitochondrial Homeostasis during Cardiac Ischemia/Reperfusion Injury
by: Lihao He, et al.
Published: (2022-07-01)

Targeting Mitochondrial Dynamics during Lower-Limb Ischemia Reperfusion in Young and Old Mice: Effect of Mitochondrial Fission Inhibitor-1 (mDivi-1)
by: Stéphanie Paradis, et al.
Published: (2024-04-01)

Mitochondria-targeted cyclosporin A delivery system to treat myocardial ischemia reperfusion injury of rats
by: Chang-xiong Zhang, et al.
Published: (2019-01-01)

Ischemia time impacts on respiratory chain functions and Ca2+-handling of cardiac subsarcolemmal mitochondria subjected to ischemia reperfusion injury
by: Marcus Leistner, et al.
Published: (2019-05-01)

The Effect of Time on Apoptosis Changes Following Ischemia-Reperfusion in Isolated Heart of Rats
by: Yusef Dostar, et al.
Published: (2017-12-01)

Platelet Contributions to Myocardial Ischemia/Reperfusion Injury
by: Nancy Schanze, et al.
Published: (2019-06-01)

Cytoprotection of rat hepatocytes by desipramine in a model of simulated ischemia/reperfusion
by: Jun-Kyu Shin, et al.
Published: (2021-09-01)

The Effect of Nerolidol Renal Dysfunction following Ischemia–Reperfusion Injury in the Rat
by: Fayez T. Hammad, et al.
Published: (2023-01-01)

Differential Roles of Mitochondrial Translocation of Active Caspase-3 and HMGB1 in Neuronal Death Induced by Status Epilepticus
by: Ji-Eun Kim, et al.
Published: (2018-09-01)

Evaluation of Porin Interaction with Adenine Nucleotide Translocase and Cyclophilin-D Proteins after Brain Ischemia and Reperfusion
by: Mohammad Ali Atlasi, et al.
Published: (2011-01-01)

Propofol Ameliorates H9c2 Cells Apoptosis Induced by Oxygen Glucose Deprivation and Reperfusion Injury via Inhibiting High Levels of Mitochondrial Fusion and Fission
by: Lidong Zhao, et al.
Published: (2019-02-01)

Isolated Mitochondria State after Myocardial Ischemia-Reperfusion Injury and Cardioprotection: Analysis by Flow Cytometry
by: Claire Crola Da Silva, et al.
Published: (2023-03-01)

Caffeic Acid Phenethyl Ester Protects Kidney Mitochondria against Ischemia/Reperfusion Induced Injury in an <i>In Vivo</i> Rat Model
by: Justina Kamarauskaite, et al.
Published: (2021-05-01)

Roles of Nitric Oxide in Brain Ischemia and Reperfusion
by: Yijie Wang, et al.
Published: (2022-04-01)

Alda-1 treatment promotes the therapeutic effect of mitochondrial transplantation for myocardial ischemia-reperfusion injury
by: Xiaolei Sun, et al.
Published: (2021-07-01)