Outcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular hole
Abstract To compare visual and anatomical outcomes between peeling and embedding of epiretinal proliferation in patients with full-thickness macular holes (FTMH) with epiretinal proliferation (EP), this retrospective cohort study classified patients into two groups based on whether EP was completely...
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| Format: | Article |
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Nature Portfolio
2024-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-58449-1 |
| _version_ | 1797209339446951936 |
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| author | Jaehwan Choi Sang Jin Kim Se Woong Kang Sungsoon Hwang Ki Young Son |
| author_facet | Jaehwan Choi Sang Jin Kim Se Woong Kang Sungsoon Hwang Ki Young Son |
| author_sort | Jaehwan Choi |
| collection | DOAJ |
| description | Abstract To compare visual and anatomical outcomes between peeling and embedding of epiretinal proliferation in patients with full-thickness macular holes (FTMH) with epiretinal proliferation (EP), this retrospective cohort study classified patients into two groups based on whether EP was completely peeled (peeling group, n = 25 eyes), or embedded into the hole (embedding group, n = 31 eyes) during surgery. Preoperative characteristics and postoperative outcomes, including best-corrected visual acuity and the length of the disrupted external limiting membrane and ellipsoid zone, were compared. Preoperative features including visual acuity and hole size did not differ between the two groups. All studied eyes achieved closure of the macular hole postoperatively. Visual acuity significantly improved at 3, 6, and 12 months postoperatively in both groups. The visual acuity 1-month after surgery was better in the embedding group than that in the peeling group (0.28 ± 0.29 vs. 0.50 ± 0.42 logarithm of the minimum angle of resolution, P = 0.016), although the difference was not noted after 3 months postoperatively. The embedding group showed shorter disruption of the external limiting membrane than the peeling group postoperatively (62.6 ± 40.2 μm vs. 326.2 ± 463.9 μm at postoperative 12 months, P = 0.045). In conclusion, the embedding technique during surgical repair of a FTMH with EP facilitates recovery of the outer foveal layers and promotes earlier restoration of visual function. |
| first_indexed | 2024-04-24T09:53:08Z |
| format | Article |
| id | doaj.art-431de2b770574472bd098dbd1e45cc73 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-24T09:53:08Z |
| publishDate | 2024-04-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj.art-431de2b770574472bd098dbd1e45cc732024-04-14T11:15:11ZengNature PortfolioScientific Reports2045-23222024-04-011411810.1038/s41598-024-58449-1Outcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular holeJaehwan Choi0Sang Jin Kim1Se Woong Kang2Sungsoon Hwang3Ki Young Son4Department of Ophthalmology, Kyung Hee University Medical Center, Kyung Hee UniversityDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Ophthalmology, Chungnam National University Sejong HospitalAbstract To compare visual and anatomical outcomes between peeling and embedding of epiretinal proliferation in patients with full-thickness macular holes (FTMH) with epiretinal proliferation (EP), this retrospective cohort study classified patients into two groups based on whether EP was completely peeled (peeling group, n = 25 eyes), or embedded into the hole (embedding group, n = 31 eyes) during surgery. Preoperative characteristics and postoperative outcomes, including best-corrected visual acuity and the length of the disrupted external limiting membrane and ellipsoid zone, were compared. Preoperative features including visual acuity and hole size did not differ between the two groups. All studied eyes achieved closure of the macular hole postoperatively. Visual acuity significantly improved at 3, 6, and 12 months postoperatively in both groups. The visual acuity 1-month after surgery was better in the embedding group than that in the peeling group (0.28 ± 0.29 vs. 0.50 ± 0.42 logarithm of the minimum angle of resolution, P = 0.016), although the difference was not noted after 3 months postoperatively. The embedding group showed shorter disruption of the external limiting membrane than the peeling group postoperatively (62.6 ± 40.2 μm vs. 326.2 ± 463.9 μm at postoperative 12 months, P = 0.045). In conclusion, the embedding technique during surgical repair of a FTMH with EP facilitates recovery of the outer foveal layers and promotes earlier restoration of visual function.https://doi.org/10.1038/s41598-024-58449-1 |
| spellingShingle | Jaehwan Choi Sang Jin Kim Se Woong Kang Sungsoon Hwang Ki Young Son Outcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular hole Scientific Reports |
| title | Outcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular hole |
| title_full | Outcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular hole |
| title_fullStr | Outcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular hole |
| title_full_unstemmed | Outcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular hole |
| title_short | Outcomes of epiretinal proliferation embedding technique in the surgery for full-thickness macular hole |
| title_sort | outcomes of epiretinal proliferation embedding technique in the surgery for full thickness macular hole |
| url | https://doi.org/10.1038/s41598-024-58449-1 |
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