Survival status and predictors of mortality from severe community-acquired pneumonia among under-five children admitted at Debre Tabor comprehensive specialized hospital: a prospective cohort study
BackgroundGlobally, Pneumonia continues to be the leading cause of mortality among under-five children. Ethiopia ranks fourth out of 15 countries worldwide in terms of the highest death rate of under-five children due to severe community-acquired pneumonia (SCAP). However, to date, there is no recen...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-06-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2023.1141366/full |
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| author | Amare Kassaw Gashaw Kerebih Shegaw Zeleke Ermias Sisay Chanie Nigatu Dessalegn Berihun Bante Asefa Ageghehu Teshome Bogale Chekole Belete Gelaw Wubet Alebachew Bayih Aragaw Tesfaw Dejen Getaneh Feleke Demewoz Kefale Molla Azmeraw Aynadis Chanie Getaneh Awoke Natnael Moges |
| author_facet | Amare Kassaw Gashaw Kerebih Shegaw Zeleke Ermias Sisay Chanie Nigatu Dessalegn Berihun Bante Asefa Ageghehu Teshome Bogale Chekole Belete Gelaw Wubet Alebachew Bayih Aragaw Tesfaw Dejen Getaneh Feleke Demewoz Kefale Molla Azmeraw Aynadis Chanie Getaneh Awoke Natnael Moges |
| author_sort | Amare Kassaw |
| collection | DOAJ |
| description | BackgroundGlobally, Pneumonia continues to be the leading cause of mortality among under-five children. Ethiopia ranks fourth out of 15 countries worldwide in terms of the highest death rate of under-five children due to severe community-acquired pneumonia (SCAP). However, to date, there is no recent study that shows survival status and predictors of mortality from SCAP. Therefore, this study aimed to determine survival status and predictors of mortality from this dangerous disease among under-five children.MethodsA facility-based prospective cohort study was conducted from 1 November 2021 to 31 October 2022 at Debre Tabor comprehensive specialized hospital. All under-five children with SCAP admitted during the study period were included. Participants were selected using a systematic sampling technique. The collected data were coded, edited, and entered into epi-data version 4.2 and then exported to STATA version 17 for further analysis. The Kaplan Meier failure estimate with log-rank test was employed to determine the survival estimates. A cox-proportional hazard regression model was fitted to identify significant variables.ResultsThe overall incidence density rate of mortality was 5.7 /1000 children with a median hospital stay of 8.2 days. Heart disease (AHR: 4.37; 95%CI: 1.68–11.32), previous admission of SCAP (AHR: 3.87; 95% CI: 1.31–11.43), WFL < −3Z score (AHR: 3.57; 95% CI: 1.02–12.42), impaired consciousness level at admission 3.41(1.14–10.19), and pleural effusion (AHR: 3.42; 95%CI: 1.18–9.93) were significant predictors of mortality.ConclusionIn this study, the survival probability of children with SCAP was low. Children with heart disease, previous admission of SCAP, WFL < −3Z score, impaired consciousness level at admission, and pleural effusion had low survival. Therefore, much emphasis is needed on children with SCAP, particularly those with identified predictors. |
| first_indexed | 2024-03-13T07:05:14Z |
| format | Article |
| id | doaj.art-4321b5be155947a78ea1fd6289ad9a43 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-03-13T07:05:14Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-4321b5be155947a78ea1fd6289ad9a432023-06-06T11:55:05ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-06-011110.3389/fped.2023.11413661141366Survival status and predictors of mortality from severe community-acquired pneumonia among under-five children admitted at Debre Tabor comprehensive specialized hospital: a prospective cohort studyAmare Kassaw0Gashaw Kerebih1Shegaw Zeleke2Ermias Sisay Chanie3Nigatu Dessalegn4Berihun Bante5Asefa Ageghehu Teshome6Bogale Chekole7Belete Gelaw8Wubet Alebachew Bayih9Aragaw Tesfaw10Dejen Getaneh Feleke11Demewoz Kefale12Molla Azmeraw13Aynadis Chanie14Getaneh Awoke15Natnael Moges16Department of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Adult Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, Mizan Tape University, Mizan Tape, EthiopiaDepartment of Adult Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Biomedical Science, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, Wolkite University, Wolkite, EthiopiaDepartment of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, Wolayta Sodo University, Wolayta, EthiopiaDepartment of Maternal and Neonatal Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Epidemiology and Biostatics, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaDepartment of Pediatrics and Child Health Nursing, College of Health Sciences, Woldia University, Woldia, Ethiopia0Department of Comprehensive Nursing, Bahir Dar University, Tibebe Gion Specialized Hospital, Bahir Dar, Ethiopia1Department of Epidemiology, Debre Tabor Health Sciences College, Debre Tabor, EthiopiaDepartment of Maternal and Neonatal Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaBackgroundGlobally, Pneumonia continues to be the leading cause of mortality among under-five children. Ethiopia ranks fourth out of 15 countries worldwide in terms of the highest death rate of under-five children due to severe community-acquired pneumonia (SCAP). However, to date, there is no recent study that shows survival status and predictors of mortality from SCAP. Therefore, this study aimed to determine survival status and predictors of mortality from this dangerous disease among under-five children.MethodsA facility-based prospective cohort study was conducted from 1 November 2021 to 31 October 2022 at Debre Tabor comprehensive specialized hospital. All under-five children with SCAP admitted during the study period were included. Participants were selected using a systematic sampling technique. The collected data were coded, edited, and entered into epi-data version 4.2 and then exported to STATA version 17 for further analysis. The Kaplan Meier failure estimate with log-rank test was employed to determine the survival estimates. A cox-proportional hazard regression model was fitted to identify significant variables.ResultsThe overall incidence density rate of mortality was 5.7 /1000 children with a median hospital stay of 8.2 days. Heart disease (AHR: 4.37; 95%CI: 1.68–11.32), previous admission of SCAP (AHR: 3.87; 95% CI: 1.31–11.43), WFL < −3Z score (AHR: 3.57; 95% CI: 1.02–12.42), impaired consciousness level at admission 3.41(1.14–10.19), and pleural effusion (AHR: 3.42; 95%CI: 1.18–9.93) were significant predictors of mortality.ConclusionIn this study, the survival probability of children with SCAP was low. Children with heart disease, previous admission of SCAP, WFL < −3Z score, impaired consciousness level at admission, and pleural effusion had low survival. Therefore, much emphasis is needed on children with SCAP, particularly those with identified predictors.https://www.frontiersin.org/articles/10.3389/fped.2023.1141366/fullunder-five childrensurvival statuspredictorspneumoniaEthiopia |
| spellingShingle | Amare Kassaw Gashaw Kerebih Shegaw Zeleke Ermias Sisay Chanie Nigatu Dessalegn Berihun Bante Asefa Ageghehu Teshome Bogale Chekole Belete Gelaw Wubet Alebachew Bayih Aragaw Tesfaw Dejen Getaneh Feleke Demewoz Kefale Molla Azmeraw Aynadis Chanie Getaneh Awoke Natnael Moges Survival status and predictors of mortality from severe community-acquired pneumonia among under-five children admitted at Debre Tabor comprehensive specialized hospital: a prospective cohort study Frontiers in Pediatrics under-five children survival status predictors pneumonia Ethiopia |
| title | Survival status and predictors of mortality from severe community-acquired pneumonia among under-five children admitted at Debre Tabor comprehensive specialized hospital: a prospective cohort study |
| title_full | Survival status and predictors of mortality from severe community-acquired pneumonia among under-five children admitted at Debre Tabor comprehensive specialized hospital: a prospective cohort study |
| title_fullStr | Survival status and predictors of mortality from severe community-acquired pneumonia among under-five children admitted at Debre Tabor comprehensive specialized hospital: a prospective cohort study |
| title_full_unstemmed | Survival status and predictors of mortality from severe community-acquired pneumonia among under-five children admitted at Debre Tabor comprehensive specialized hospital: a prospective cohort study |
| title_short | Survival status and predictors of mortality from severe community-acquired pneumonia among under-five children admitted at Debre Tabor comprehensive specialized hospital: a prospective cohort study |
| title_sort | survival status and predictors of mortality from severe community acquired pneumonia among under five children admitted at debre tabor comprehensive specialized hospital a prospective cohort study |
| topic | under-five children survival status predictors pneumonia Ethiopia |
| url | https://www.frontiersin.org/articles/10.3389/fped.2023.1141366/full |
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