Occupational Health Aspects with Special Focus on Physiological Differences between Office and Metalworkers
Physical workload adversely impacts inflammation, oxidative stress and mood in heavy workers. We compared these risk parameters between metalworkers (<i>n</i> = 20) and office workers (<i>n =</i> 30), including gender differences. Blood samples were analyzed with thirty param...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/11/4/633 |
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| author | Franz Tatzber Sieglinde Zelzer Barbara Obermayer-Pietsch Stefan Rinnerhofer Michael Kundi Gerhard Cvirn Georg Wultsch Markus Herrmann Harald Mangge Tobias Niedrist Willibald Wonisch |
| author_facet | Franz Tatzber Sieglinde Zelzer Barbara Obermayer-Pietsch Stefan Rinnerhofer Michael Kundi Gerhard Cvirn Georg Wultsch Markus Herrmann Harald Mangge Tobias Niedrist Willibald Wonisch |
| author_sort | Franz Tatzber |
| collection | DOAJ |
| description | Physical workload adversely impacts inflammation, oxidative stress and mood in heavy workers. We compared these risk parameters between metalworkers (<i>n</i> = 20) and office workers (<i>n =</i> 30), including gender differences. Blood samples were analyzed with thirty parameters to overview endocrinology, inflammation, and psychological and oxidative stress. Despite an adequate antioxidative supply, oxidative stress occurred in metalworkers, as indicated by significantly increased peroxide and homocysteine (Hcy) levels. Moreover, increased concentrations were observed in this group regarding psychological stress and diet-related parameters. Sex-specific differences were determined for physical dimensions, dehydroepiandrosterone sulfate (DHEAS), Hcy, uric acid, triglycerides, osmolality, anti-Mullerian hormone (AMH) and testosterone. Age-associated differences were observed for DHEAS, glycosylated hemoglobin, adrenaline, AMH and testosterone. In male office workers, the body mass index was associated with increased LDL-HDL, cholesterol-HDL and homeostatic model assessment of insulin resistance (HOMA-IR). In conclusion, these results indicate increased oxidative stress and psychological stress in heavy workers independently of adequate antioxidant sustenance. The sedentary occupation of office workers, in turn, favored diseases of affluence. This might be particularly relevant for long-term occupied persons and older workers due to a hormonal shift coming along, given the risk for oxidative stress-related diseases such as cardiovascular disease, particularly in the case of males, based on their lifestyle habits. |
| first_indexed | 2024-03-09T11:14:47Z |
| format | Article |
| id | doaj.art-432284aefbc348b98b2bd97795ede70a |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-09T11:14:47Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-432284aefbc348b98b2bd97795ede70a2023-12-01T00:34:03ZengMDPI AGAntioxidants2076-39212022-03-0111463310.3390/antiox11040633Occupational Health Aspects with Special Focus on Physiological Differences between Office and MetalworkersFranz Tatzber0Sieglinde Zelzer1Barbara Obermayer-Pietsch2Stefan Rinnerhofer3Michael Kundi4Gerhard Cvirn5Georg Wultsch6Markus Herrmann7Harald Mangge8Tobias Niedrist9Willibald Wonisch10Otto Loewi Research Center, Division of Immunology and Pathophysiology, Medical University of Graz, Heinrichstraße 31a, 8010 Graz, AustriaClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, AustriaEndocrinology Lab Platform, Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, AustriaExercise Physiology, Training and Training Therapy Research Group, Institute of Sports Science, University of Graz, Mozartgasse 14, 8010 Graz, AustriaCenter for Public Health, Department of Environmental Health, Medical University of Vienna, Kinderspitalgasse 15, 1090 Vienna, AustriaOtto Loewi Research Center, Division of Physiological Chemistry, Medical University of Graz, Neue Stiftingtalstraße 6 HBK M1/D3, 8010 Graz, AustriaArbeitsmedizinisches Institut Graz, Herrgottwiesgasse 149, 8055 Graz, AustriaClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, AustriaClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, AustriaClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, AustriaOtto Loewi Research Center, Division of Physiological Chemistry, Medical University of Graz, Neue Stiftingtalstraße 6 HBK M1/D3, 8010 Graz, AustriaPhysical workload adversely impacts inflammation, oxidative stress and mood in heavy workers. We compared these risk parameters between metalworkers (<i>n</i> = 20) and office workers (<i>n =</i> 30), including gender differences. Blood samples were analyzed with thirty parameters to overview endocrinology, inflammation, and psychological and oxidative stress. Despite an adequate antioxidative supply, oxidative stress occurred in metalworkers, as indicated by significantly increased peroxide and homocysteine (Hcy) levels. Moreover, increased concentrations were observed in this group regarding psychological stress and diet-related parameters. Sex-specific differences were determined for physical dimensions, dehydroepiandrosterone sulfate (DHEAS), Hcy, uric acid, triglycerides, osmolality, anti-Mullerian hormone (AMH) and testosterone. Age-associated differences were observed for DHEAS, glycosylated hemoglobin, adrenaline, AMH and testosterone. In male office workers, the body mass index was associated with increased LDL-HDL, cholesterol-HDL and homeostatic model assessment of insulin resistance (HOMA-IR). In conclusion, these results indicate increased oxidative stress and psychological stress in heavy workers independently of adequate antioxidant sustenance. The sedentary occupation of office workers, in turn, favored diseases of affluence. This might be particularly relevant for long-term occupied persons and older workers due to a hormonal shift coming along, given the risk for oxidative stress-related diseases such as cardiovascular disease, particularly in the case of males, based on their lifestyle habits.https://www.mdpi.com/2076-3921/11/4/633oxidative stresssex-specific differencestaxing workexhaustionwhite-collar workerblue-collar worker |
| spellingShingle | Franz Tatzber Sieglinde Zelzer Barbara Obermayer-Pietsch Stefan Rinnerhofer Michael Kundi Gerhard Cvirn Georg Wultsch Markus Herrmann Harald Mangge Tobias Niedrist Willibald Wonisch Occupational Health Aspects with Special Focus on Physiological Differences between Office and Metalworkers Antioxidants oxidative stress sex-specific differences taxing work exhaustion white-collar worker blue-collar worker |
| title | Occupational Health Aspects with Special Focus on Physiological Differences between Office and Metalworkers |
| title_full | Occupational Health Aspects with Special Focus on Physiological Differences between Office and Metalworkers |
| title_fullStr | Occupational Health Aspects with Special Focus on Physiological Differences between Office and Metalworkers |
| title_full_unstemmed | Occupational Health Aspects with Special Focus on Physiological Differences between Office and Metalworkers |
| title_short | Occupational Health Aspects with Special Focus on Physiological Differences between Office and Metalworkers |
| title_sort | occupational health aspects with special focus on physiological differences between office and metalworkers |
| topic | oxidative stress sex-specific differences taxing work exhaustion white-collar worker blue-collar worker |
| url | https://www.mdpi.com/2076-3921/11/4/633 |
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