State of the Art of Chemosensors in a Biomedical Context
Healthcare is undergoing large transformations, and it is imperative to leverage new technologies to support the advent of personalized medicine and disease prevention. It is now well accepted that the levels of certain biological molecules found in blood and other bodily fluids, as well as in exhal...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Chemosensors |
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| Online Access: | https://www.mdpi.com/2227-9040/10/6/199 |
| _version_ | 1797488838105366528 |
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| author | Erich Kny Ciril Reiner-Rozman Jakub Dostalek Achim-Walter Hassel Christa Nöhammer Florian Pfaffeneder-Mantai Sabine Szunerits Viktoria Weber Wolfgang Knoll Christoph Kleber |
| author_facet | Erich Kny Ciril Reiner-Rozman Jakub Dostalek Achim-Walter Hassel Christa Nöhammer Florian Pfaffeneder-Mantai Sabine Szunerits Viktoria Weber Wolfgang Knoll Christoph Kleber |
| author_sort | Erich Kny |
| collection | DOAJ |
| description | Healthcare is undergoing large transformations, and it is imperative to leverage new technologies to support the advent of personalized medicine and disease prevention. It is now well accepted that the levels of certain biological molecules found in blood and other bodily fluids, as well as in exhaled breath, are an indication of the onset of many human diseases and reflect the health status of the person. Blood, urine, sweat, or saliva biomarkers can therefore serve in early diagnosis of diseases such as cancer, but also in monitoring disease progression, detecting metabolic disfunctions, and predicting response to a given therapy. For most point-of-care sensors, the requirement that patients themselves can use and apply them is crucial not only regarding the diagnostic part, but also at the sample collection level. This has stimulated the development of such diagnostic approaches for the non-invasive analysis of disease-relevant analytes. Considering these timely efforts, this review article focuses on novel, sensitive, and selective sensing systems for the detection of different endogenous target biomarkers in bodily fluids as well as in exhaled breath, which are associated with human diseases. |
| first_indexed | 2024-03-10T00:09:00Z |
| format | Article |
| id | doaj.art-43239ad51e0c4a588fd42a00a5541c23 |
| institution | Directory Open Access Journal |
| issn | 2227-9040 |
| language | English |
| last_indexed | 2024-03-10T00:09:00Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemosensors |
| spelling | doaj.art-43239ad51e0c4a588fd42a00a5541c232023-11-23T16:03:48ZengMDPI AGChemosensors2227-90402022-05-0110619910.3390/chemosensors10060199State of the Art of Chemosensors in a Biomedical ContextErich Kny0Ciril Reiner-Rozman1Jakub Dostalek2Achim-Walter Hassel3Christa Nöhammer4Florian Pfaffeneder-Mantai5Sabine Szunerits6Viktoria Weber7Wolfgang Knoll8Christoph Kleber9Research Division for Chemistry and Physics of Materials, Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University, Steiner Landstrasse 124, 3500 Krems, AustriaResearch Division for Chemistry and Physics of Materials, Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University, Steiner Landstrasse 124, 3500 Krems, AustriaBiosensor Technologies, AIT Austrian Institute of Technology GmbH, Konrad-Lorenz-Straße 24, 3430 Tulln an der Donau, AustriaInstitute of Chemical Technology of Inorganic Materials, Johannes-Kepler-University Linz (JKU), Altenberger Strasse 69, 4040 Linz, AustriaMolecular Diagnostics, AIT Austrian Institute of Technology GmbH, Giefinggasse 4, 1210 Vienna, AustriaResearch Division for Chemistry and Physics of Materials, Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University, Steiner Landstrasse 124, 3500 Krems, AustriaUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520-IEMN, F-59000 Lille, FranceDepartment for Biomedical Research, University of Continuing Education Krems, 3500 Krems, AustriaBiosensor Technologies, AIT Austrian Institute of Technology GmbH, Konrad-Lorenz-Straße 24, 3430 Tulln an der Donau, AustriaResearch Division for Chemistry and Physics of Materials, Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University, Steiner Landstrasse 124, 3500 Krems, AustriaHealthcare is undergoing large transformations, and it is imperative to leverage new technologies to support the advent of personalized medicine and disease prevention. It is now well accepted that the levels of certain biological molecules found in blood and other bodily fluids, as well as in exhaled breath, are an indication of the onset of many human diseases and reflect the health status of the person. Blood, urine, sweat, or saliva biomarkers can therefore serve in early diagnosis of diseases such as cancer, but also in monitoring disease progression, detecting metabolic disfunctions, and predicting response to a given therapy. For most point-of-care sensors, the requirement that patients themselves can use and apply them is crucial not only regarding the diagnostic part, but also at the sample collection level. This has stimulated the development of such diagnostic approaches for the non-invasive analysis of disease-relevant analytes. Considering these timely efforts, this review article focuses on novel, sensitive, and selective sensing systems for the detection of different endogenous target biomarkers in bodily fluids as well as in exhaled breath, which are associated with human diseases.https://www.mdpi.com/2227-9040/10/6/199medical diagnosticsbiosensorplasmonicssurface plasmon resonancesingle molecule detectionsensors |
| spellingShingle | Erich Kny Ciril Reiner-Rozman Jakub Dostalek Achim-Walter Hassel Christa Nöhammer Florian Pfaffeneder-Mantai Sabine Szunerits Viktoria Weber Wolfgang Knoll Christoph Kleber State of the Art of Chemosensors in a Biomedical Context Chemosensors medical diagnostics biosensor plasmonics surface plasmon resonance single molecule detection sensors |
| title | State of the Art of Chemosensors in a Biomedical Context |
| title_full | State of the Art of Chemosensors in a Biomedical Context |
| title_fullStr | State of the Art of Chemosensors in a Biomedical Context |
| title_full_unstemmed | State of the Art of Chemosensors in a Biomedical Context |
| title_short | State of the Art of Chemosensors in a Biomedical Context |
| title_sort | state of the art of chemosensors in a biomedical context |
| topic | medical diagnostics biosensor plasmonics surface plasmon resonance single molecule detection sensors |
| url | https://www.mdpi.com/2227-9040/10/6/199 |
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