Mechanisms of Reactivation and Its Interaction with
The telomerase reverse transcriptase (TERT) gene, which is repressed in most differentiated human cells, can be reactivated by somatic TERT alterations and epigenetic modulations. Moreover, the recruitment, accessibility, and binding of transcription factors also affect the regulation of TERT expres...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Korean Endocrine Society
2020-09-01
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Series: | Endocrinology and Metabolism |
Subjects: | |
Online Access: | http://www.e-enm.org/upload/pdf/enm-2020-304.pdf |