AN ALGORITHM FOR DATA QUALITY ASSESSMENT IN PREDICTIVE TOXICOLOGY
Lack of the quality of the information that is integrated from heterogeneous sources is an important issue in many scientific domains. In toxicology the importance is even greater since the data is used for Quantitative Structure Activity Relationship (QSAR) modeling for prediction of chemical toxi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Gdańsk University of Technology
2007-01-01
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| Series: | TASK Quarterly |
| Subjects: | |
| Online Access: | https://journal.mostwiedzy.pl/TASKQuarterly/article/view/2082 |
| _version_ | 1817984252366553088 |
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| author | LADAN MALAZIZI DANIEL NEAGU QASIM CHAUDHRY |
| author_facet | LADAN MALAZIZI DANIEL NEAGU QASIM CHAUDHRY |
| author_sort | LADAN MALAZIZI |
| collection | DOAJ |
| description |
Lack of the quality of the information that is integrated from heterogeneous sources is an important issue in many scientific domains. In toxicology the importance is even greater since the data is used for Quantitative Structure Activity Relationship (QSAR) modeling for prediction of chemical toxicity of new compounds. Much work has been done on QSARs but little attention has been paid to the quality of the data used. The underlying concept points to the absence of the quality criteria framework in this domain. This paper presents a review on some of the existing data quality assessment methods in various domains and their relevance and possible application to predictive toxicology, highlights number of data quality deficiencies from experimental work on internal data and also proposes some quality metrics and an algorithm for assessing data quality concluded from the results.
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| first_indexed | 2024-04-13T23:43:16Z |
| format | Article |
| id | doaj.art-432a3a327b504fdeba7e764aa6c9bb14 |
| institution | Directory Open Access Journal |
| issn | 1428-6394 |
| language | English |
| last_indexed | 2024-04-13T23:43:16Z |
| publishDate | 2007-01-01 |
| publisher | Gdańsk University of Technology |
| record_format | Article |
| series | TASK Quarterly |
| spelling | doaj.art-432a3a327b504fdeba7e764aa6c9bb142022-12-22T02:24:25ZengGdańsk University of TechnologyTASK Quarterly1428-63942007-01-01111-2AN ALGORITHM FOR DATA QUALITY ASSESSMENT IN PREDICTIVE TOXICOLOGYLADAN MALAZIZI0DANIEL NEAGU1QASIM CHAUDHRY2University of Bradford, Department of Computing, School of InformaticsUniversity of Bradford, Department of Computing, School of InformaticsCentral Science Laboratory Lack of the quality of the information that is integrated from heterogeneous sources is an important issue in many scientific domains. In toxicology the importance is even greater since the data is used for Quantitative Structure Activity Relationship (QSAR) modeling for prediction of chemical toxicity of new compounds. Much work has been done on QSARs but little attention has been paid to the quality of the data used. The underlying concept points to the absence of the quality criteria framework in this domain. This paper presents a review on some of the existing data quality assessment methods in various domains and their relevance and possible application to predictive toxicology, highlights number of data quality deficiencies from experimental work on internal data and also proposes some quality metrics and an algorithm for assessing data quality concluded from the results. https://journal.mostwiedzy.pl/TASKQuarterly/article/view/2082QSAR modelsdata qualitydata cleaning |
| spellingShingle | LADAN MALAZIZI DANIEL NEAGU QASIM CHAUDHRY AN ALGORITHM FOR DATA QUALITY ASSESSMENT IN PREDICTIVE TOXICOLOGY TASK Quarterly QSAR models data quality data cleaning |
| title | AN ALGORITHM FOR DATA QUALITY ASSESSMENT IN PREDICTIVE TOXICOLOGY |
| title_full | AN ALGORITHM FOR DATA QUALITY ASSESSMENT IN PREDICTIVE TOXICOLOGY |
| title_fullStr | AN ALGORITHM FOR DATA QUALITY ASSESSMENT IN PREDICTIVE TOXICOLOGY |
| title_full_unstemmed | AN ALGORITHM FOR DATA QUALITY ASSESSMENT IN PREDICTIVE TOXICOLOGY |
| title_short | AN ALGORITHM FOR DATA QUALITY ASSESSMENT IN PREDICTIVE TOXICOLOGY |
| title_sort | algorithm for data quality assessment in predictive toxicology |
| topic | QSAR models data quality data cleaning |
| url | https://journal.mostwiedzy.pl/TASKQuarterly/article/view/2082 |
| work_keys_str_mv | AT ladanmalazizi analgorithmfordataqualityassessmentinpredictivetoxicology AT danielneagu analgorithmfordataqualityassessmentinpredictivetoxicology AT qasimchaudhry analgorithmfordataqualityassessmentinpredictivetoxicology AT ladanmalazizi algorithmfordataqualityassessmentinpredictivetoxicology AT danielneagu algorithmfordataqualityassessmentinpredictivetoxicology AT qasimchaudhry algorithmfordataqualityassessmentinpredictivetoxicology |