Algorithmic fairness in computational medicine

Summary: Machine learning models are increasingly adopted for facilitating clinical decision-making. However, recent research has shown that machine learning techniques may result in potential biases when making decisions for people in different subgroups, which can lead to detrimental effects on th...

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Main Authors: Jie Xu, Yunyu Xiao, Wendy Hui Wang, Yue Ning, Elizabeth A. Shenkman, Jiang Bian, Fei Wang
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422004327
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author Jie Xu
Yunyu Xiao
Wendy Hui Wang
Yue Ning
Elizabeth A. Shenkman
Jiang Bian
Fei Wang
author_facet Jie Xu
Yunyu Xiao
Wendy Hui Wang
Yue Ning
Elizabeth A. Shenkman
Jiang Bian
Fei Wang
author_sort Jie Xu
collection DOAJ
description Summary: Machine learning models are increasingly adopted for facilitating clinical decision-making. However, recent research has shown that machine learning techniques may result in potential biases when making decisions for people in different subgroups, which can lead to detrimental effects on the health and well-being of specific demographic groups such as vulnerable ethnic minorities. This problem, termed algorithmic bias, has been extensively studied in theoretical machine learning recently. However, the impact of algorithmic bias on medicine and methods to mitigate this bias remain topics of active discussion. This paper presents a comprehensive review of algorithmic fairness in the context of computational medicine, which aims at improving medicine with computational approaches. Specifically, we overview the different types of algorithmic bias, fairness quantification metrics, and bias mitigation methods, and summarize popular software libraries and tools for bias evaluation and mitigation, with the goal of providing reference and insights to researchers and practitioners in computational medicine.
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spelling doaj.art-432d6720db7148d2afaf33d6d7469cd42022-12-22T04:02:47ZengElsevierEBioMedicine2352-39642022-10-0184104250Algorithmic fairness in computational medicineJie Xu0Yunyu Xiao1Wendy Hui Wang2Yue Ning3Elizabeth A. Shenkman4Jiang Bian5Fei Wang6Department of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USADepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USADepartment of Computer Science, Stevens Institute of Technology, Hoboken, NJ, USADepartment of Computer Science, Stevens Institute of Technology, Hoboken, NJ, USADepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USADepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USADepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA; Corresponding author.Summary: Machine learning models are increasingly adopted for facilitating clinical decision-making. However, recent research has shown that machine learning techniques may result in potential biases when making decisions for people in different subgroups, which can lead to detrimental effects on the health and well-being of specific demographic groups such as vulnerable ethnic minorities. This problem, termed algorithmic bias, has been extensively studied in theoretical machine learning recently. However, the impact of algorithmic bias on medicine and methods to mitigate this bias remain topics of active discussion. This paper presents a comprehensive review of algorithmic fairness in the context of computational medicine, which aims at improving medicine with computational approaches. Specifically, we overview the different types of algorithmic bias, fairness quantification metrics, and bias mitigation methods, and summarize popular software libraries and tools for bias evaluation and mitigation, with the goal of providing reference and insights to researchers and practitioners in computational medicine.http://www.sciencedirect.com/science/article/pii/S2352396422004327Algorithmic fairnessComputational medicine
spellingShingle Jie Xu
Yunyu Xiao
Wendy Hui Wang
Yue Ning
Elizabeth A. Shenkman
Jiang Bian
Fei Wang
Algorithmic fairness in computational medicine
EBioMedicine
Algorithmic fairness
Computational medicine
title Algorithmic fairness in computational medicine
title_full Algorithmic fairness in computational medicine
title_fullStr Algorithmic fairness in computational medicine
title_full_unstemmed Algorithmic fairness in computational medicine
title_short Algorithmic fairness in computational medicine
title_sort algorithmic fairness in computational medicine
topic Algorithmic fairness
Computational medicine
url http://www.sciencedirect.com/science/article/pii/S2352396422004327
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AT yunyuxiao algorithmicfairnessincomputationalmedicine
AT wendyhuiwang algorithmicfairnessincomputationalmedicine
AT yuening algorithmicfairnessincomputationalmedicine
AT elizabethashenkman algorithmicfairnessincomputationalmedicine
AT jiangbian algorithmicfairnessincomputationalmedicine
AT feiwang algorithmicfairnessincomputationalmedicine