| Summary: | OBJECTIVE. The aim of this study was to improve the results of the complex treatment of early periprosthetic infection in hip replacement by using a vacuum therapy. MATERIAL AND METHODS. The study included 82 patients with periprosthetic infection who had been hospitalized to the department of traumatology and orthopedics federal state budgetary educational Institution of higher education «north-Western state Medical University named after I. I. Mechnikov» from 2008 to 2016. We compared the results of the treatment in the retrospective group (without vacuum therapy) and in the prospective panel (using the local negative pressure method). RESULTS. The studies demonstrated the efficacy of the method of vacuum therapy in combination with standard methods of periprosthetic infection treatment. The clinical effects were: decrease of tissue edema, good reduction of wound exudate, decreasing the concentration of the microflora in the surgical wound area, granulation growth, stimulation of epithelialization, reducing of the time spent in the hospital. CONCLUSION. All these effects lead to the fact that the number of cases where we were able to maintain the implant increased from 52,9 % in retrospective groups to 78,8 % in prospective groups.
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