Naldemedine is effective in the treatment of opioid-induced constipation in patients with chronic non-cancer pain who had a poor response to laxatives
Background: Two studies demonstrated the efficacy and safety of naldemedine in adult patients with chronic non-cancer pain and opioid-induced constipation (OIC). However, no studies have compared the efficacy of peripherally acting µ-opioid receptor antagonists in patients with adequate and inadequa...
Main Authors: | Martin E. Hale, James E. Wild, Tadaaki Yamada, Takaaki Yokota, Jan Tack, Viola Andresen, Asbjørn Mohr Drewes |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-07-01
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Series: | Therapeutic Advances in Gastroenterology |
Online Access: | https://doi.org/10.1177/17562848211032320 |
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