Modulation of LPS-Induced Neurodegeneration by Intestinal Helminth Infection in Ageing Mice

Modulation of LPS-Induced Neurodegeneration by Intestinal Helminth Infection in Ageing Mice

Parasitic helminths induce a transient, short-term inflammation at the beginning of infection, but in persistent infection may suppress the systemic immune response by enhancing the activity of regulatory M2 macrophages. The aim of the study was to determine how nematode infection affects age-relate...

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Bibliographic Details
Main Authors: Natalia Jermakow, Weronika Skarżyńska, Katarzyna Lewandowska, Ewelina Kiernozek, Katarzyna Goździk, Anna Mietelska-Porowska, Nadzieja Drela, Urszula Wojda, Maria Doligalska
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
helminths
persistent infection
neuroinflammation
ageing
neurodegenerative diseases
immunomodulation
Online Access:https://www.mdpi.com/1422-0067/24/18/13994

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