Incorporation of Pharmacist in Conducting Medication Reviews for Identification of Risk of QT Prolongation: A Neglecting Latent Approach in Cardiology

Sudden cardiac arrest correlates with QT-interval prolongation and torsade de points (TdP). Several medicines frequently used in geriatric aged care populations can cause QT prolongation. Major predisposing factors and QT-prolonging medications enhance QT interval prolongation incidence in medical...

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Main Authors: Ahmad Ullah Hamza, Kashif Rizvi, Kashif Ali
Format: Article
Language:English
Published: Research Center for Rational Use of Drugs (RCRUD) 2022-10-01
Series:Journal of Pharmaceutical Care
Subjects:
Online Access:https://jpc.tums.ac.ir/index.php/jpc/article/view/482
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author Ahmad Ullah Hamza
Kashif Rizvi
Kashif Ali
author_facet Ahmad Ullah Hamza
Kashif Rizvi
Kashif Ali
author_sort Ahmad Ullah Hamza
collection DOAJ
description Sudden cardiac arrest correlates with QT-interval prolongation and torsade de points (TdP). Several medicines frequently used in geriatric aged care populations can cause QT prolongation. Major predisposing factors and QT-prolonging medications enhance QT interval prolongation incidence in medical inpatients. Pharmacists can help ensure safe drug therapy and in-hospital patient safety by paying attention to QT prolongation and extra risk factors for prolonged QT intervals during medication reconciliation. We recommend pharmacists improve knowledge and awareness of corrected QT prolongation (QTc) when conducting drug reviews. Implementation of Pharmacist-driven QTc monitoring is required to lower the risk of QTc prolongation.
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spelling doaj.art-433ab77629454789888bb07d67edbbc92022-12-22T04:07:21ZengResearch Center for Rational Use of Drugs (RCRUD)Journal of Pharmaceutical Care2322-46302322-45092022-10-0110310.18502/jpc.v10i3.10798Incorporation of Pharmacist in Conducting Medication Reviews for Identification of Risk of QT Prolongation: A Neglecting Latent Approach in CardiologyAhmad Ullah Hamza0Kashif Rizvi1Kashif Ali2National Institute of Cardiovascular Diseases, Karachi, Pakistan.King Faisal Specialist Hospital and Research Centre, Karachi, Pakistan.Dow University of Health Sciences, Karachi, Pakistan. Sudden cardiac arrest correlates with QT-interval prolongation and torsade de points (TdP). Several medicines frequently used in geriatric aged care populations can cause QT prolongation. Major predisposing factors and QT-prolonging medications enhance QT interval prolongation incidence in medical inpatients. Pharmacists can help ensure safe drug therapy and in-hospital patient safety by paying attention to QT prolongation and extra risk factors for prolonged QT intervals during medication reconciliation. We recommend pharmacists improve knowledge and awareness of corrected QT prolongation (QTc) when conducting drug reviews. Implementation of Pharmacist-driven QTc monitoring is required to lower the risk of QTc prolongation. https://jpc.tums.ac.ir/index.php/jpc/article/view/482QT Interval ProlongationDrug-Drug InteractionPharmacists; Cardiology
spellingShingle Ahmad Ullah Hamza
Kashif Rizvi
Kashif Ali
Incorporation of Pharmacist in Conducting Medication Reviews for Identification of Risk of QT Prolongation: A Neglecting Latent Approach in Cardiology
Journal of Pharmaceutical Care
QT Interval Prolongation
Drug-Drug Interaction
Pharmacists; Cardiology
title Incorporation of Pharmacist in Conducting Medication Reviews for Identification of Risk of QT Prolongation: A Neglecting Latent Approach in Cardiology
title_full Incorporation of Pharmacist in Conducting Medication Reviews for Identification of Risk of QT Prolongation: A Neglecting Latent Approach in Cardiology
title_fullStr Incorporation of Pharmacist in Conducting Medication Reviews for Identification of Risk of QT Prolongation: A Neglecting Latent Approach in Cardiology
title_full_unstemmed Incorporation of Pharmacist in Conducting Medication Reviews for Identification of Risk of QT Prolongation: A Neglecting Latent Approach in Cardiology
title_short Incorporation of Pharmacist in Conducting Medication Reviews for Identification of Risk of QT Prolongation: A Neglecting Latent Approach in Cardiology
title_sort incorporation of pharmacist in conducting medication reviews for identification of risk of qt prolongation a neglecting latent approach in cardiology
topic QT Interval Prolongation
Drug-Drug Interaction
Pharmacists; Cardiology
url https://jpc.tums.ac.ir/index.php/jpc/article/view/482
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