Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays
<p>Abstract</p> <p>Background</p> <p>Genomic hybridization platforms, including BAC-CGH and genotyping arrays, have been used to estimate chromosome copy number (CN) in tumor samples by detecting the relative strength of genomic signal. The methods rely on the assumptio...
Main Authors: | Cowell John K, Lee Walter, Lo Ken C, Gardina Paul J, Turpaz Yaron |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-10-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/9/489 |
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