Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula

Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula

Objective: We examined if renal denervation (RDN) attenuates the progression of aortocaval fistula (ACF)-induced heart failure or improves renal hemodynamics in Ren-2 transgenic rats (TGR), a model of angiotensin II (ANG II)-dependent hypertension. Methods: Bilateral RDN was performed 1 week after c...

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Main Authors: Zuzana Honetschlagerová, Olga Gawrys, Šárka Jíchová, Petra Škaroupková, Soňa Kikerlová, Zdeňka Vaňourková, Zuzana Husková, Vojtěch Melenovský, Elzbieta Kompanowska-Jezierska, Janusz Sadowski, František Kolář, Jiří Novotný, Lucie Hejnová, Petr Kujal, Luděk Červenka
Format: Article
Language:English
Published: Karger Publishers 2021-02-01
Series:Kidney & Blood Pressure Research
Subjects:
congestive heart failure
hypertension
aortocaval fistula
renal blood flow
renal vascular reactivity
angiotensin ii
renal denervation
Online Access:https://www.karger.com/Article/FullText/513071

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