Characterization and Functionalization Approaches for the Study of Polymeric Nanoparticles: The State of the Art in Italian Research
Polymeric nanoparticles (PNPs) are a group of nanocarriers employed in a wide range of applications. Characterization is a fundamental step in PNPs formulation and many basic techniques are available to provide chemical-physical information such as dimensions, surface potential, stability and solubi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Micro |
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| Online Access: | https://www.mdpi.com/2673-8023/3/1/2 |
| _version_ | 1827748674472509440 |
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| author | Biagio Todaro Melissa Santi |
| author_facet | Biagio Todaro Melissa Santi |
| author_sort | Biagio Todaro |
| collection | DOAJ |
| description | Polymeric nanoparticles (PNPs) are a group of nanocarriers employed in a wide range of applications. Characterization is a fundamental step in PNPs formulation and many basic techniques are available to provide chemical-physical information such as dimensions, surface potential, stability and solubility. Recently, these techniques have been implemented with more innovative ones to obtain more precise knowledge of the nanomaterials. In this review we analyzed the state of the art in the field of polymeric nanoparticles produced by Italian laboratories. We described all methods available for PNPs characterization with their applications as drug delivery systems. We also reported the different types of molecules that were recently used for PNPs functionalization, a fundamental step in delivering drugs specifically to their targets and then resulting in reduced side effects in patients. |
| first_indexed | 2024-03-11T06:10:04Z |
| format | Article |
| id | doaj.art-434cd2a17cdb4986b2d18afb7dc5f410 |
| institution | Directory Open Access Journal |
| issn | 2673-8023 |
| language | English |
| last_indexed | 2024-03-11T06:10:04Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micro |
| spelling | doaj.art-434cd2a17cdb4986b2d18afb7dc5f4102023-11-17T12:40:50ZengMDPI AGMicro2673-80232022-12-013192110.3390/micro3010002Characterization and Functionalization Approaches for the Study of Polymeric Nanoparticles: The State of the Art in Italian ResearchBiagio Todaro0Melissa Santi1NEST Laboratory, Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyNEST, Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyPolymeric nanoparticles (PNPs) are a group of nanocarriers employed in a wide range of applications. Characterization is a fundamental step in PNPs formulation and many basic techniques are available to provide chemical-physical information such as dimensions, surface potential, stability and solubility. Recently, these techniques have been implemented with more innovative ones to obtain more precise knowledge of the nanomaterials. In this review we analyzed the state of the art in the field of polymeric nanoparticles produced by Italian laboratories. We described all methods available for PNPs characterization with their applications as drug delivery systems. We also reported the different types of molecules that were recently used for PNPs functionalization, a fundamental step in delivering drugs specifically to their targets and then resulting in reduced side effects in patients.https://www.mdpi.com/2673-8023/3/1/2polymeric nanoparticlesdrug delivery systemscharacterization methodstargeting moietiesItalian researchItaly |
| spellingShingle | Biagio Todaro Melissa Santi Characterization and Functionalization Approaches for the Study of Polymeric Nanoparticles: The State of the Art in Italian Research Micro polymeric nanoparticles drug delivery systems characterization methods targeting moieties Italian research Italy |
| title | Characterization and Functionalization Approaches for the Study of Polymeric Nanoparticles: The State of the Art in Italian Research |
| title_full | Characterization and Functionalization Approaches for the Study of Polymeric Nanoparticles: The State of the Art in Italian Research |
| title_fullStr | Characterization and Functionalization Approaches for the Study of Polymeric Nanoparticles: The State of the Art in Italian Research |
| title_full_unstemmed | Characterization and Functionalization Approaches for the Study of Polymeric Nanoparticles: The State of the Art in Italian Research |
| title_short | Characterization and Functionalization Approaches for the Study of Polymeric Nanoparticles: The State of the Art in Italian Research |
| title_sort | characterization and functionalization approaches for the study of polymeric nanoparticles the state of the art in italian research |
| topic | polymeric nanoparticles drug delivery systems characterization methods targeting moieties Italian research Italy |
| url | https://www.mdpi.com/2673-8023/3/1/2 |
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