The association of isoconazole–diflucortolone in the treatment of pediatric tinea corporis
Background: Tinea corporis is a common mycotic infection in children. Staphylococcus aureus superinfections may be observed in atopic children with tinea corporis suffering from severe pruritus and consequent scratching. Objective: From 2006 to 2011, we observed 288 children with mycologically prove...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2018-02-01
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| Series: | Journal of Dermatological Treatment |
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| Online Access: | http://dx.doi.org/10.1080/09546634.2017.1360988 |
| _version_ | 1797683732349452288 |
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| author | Stefano Veraldi Rossana Schianchi Paolo Pontini Alberto Gorani |
| author_facet | Stefano Veraldi Rossana Schianchi Paolo Pontini Alberto Gorani |
| author_sort | Stefano Veraldi |
| collection | DOAJ |
| description | Background: Tinea corporis is a common mycotic infection in children. Staphylococcus aureus superinfections may be observed in atopic children with tinea corporis suffering from severe pruritus and consequent scratching. Objective: From 2006 to 2011, we observed 288 children with mycologically proven tinea corporis. In 39 of them (13.5%) tinea corporis was superinfected by S. aureus: all these children were affected by atopic dermatitis. We interpreted these bacterial superinfections as the clinical result of scratching due to pruritus. Methods: In 2012, we decided to treat all children with a single lesion of tinea corporis with a combination of 1% isoconazole nitrate and 0.1% diflucortolone valerate cream (one application/day for 5–7 days), followed by a treatment with isoconazole or clotrimazole or ciclopirox cream (two applications/day for two weeks). Results: From 2012 to 2014, we observed 108 children with tinea corporis confirmed by mycological examinations. Clinical and mycological recovery was observed in 93 of them (86.1%). Only four of these children (3.7%) developed S. aureus superinfections. Conclusions: Our study in atopic children with tinea corporis superinfected by S. aureus confirms that a topical therapy with the association isoconazole–diflucortolone is useful and safe. |
| first_indexed | 2024-03-12T00:19:02Z |
| format | Article |
| id | doaj.art-434ff1f1b4bc4c81ac6b979bc81ac82f |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2024-03-12T00:19:02Z |
| publishDate | 2018-02-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-434ff1f1b4bc4c81ac6b979bc81ac82f2023-09-15T14:08:31ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532018-02-0129220020110.1080/09546634.2017.13609881360988The association of isoconazole–diflucortolone in the treatment of pediatric tinea corporisStefano Veraldi0Rossana Schianchi1Paolo Pontini2Alberto Gorani3Università degli Studi di Milano, I.R.C.C.S. Foundation, Cà Granda Ospedale Maggiore PoliclinicoCentro Dermatologico Milanese (C.D.M.)Università degli Studi di Milano, I.R.C.C.S. Foundation, Cà Granda Ospedale Maggiore PoliclinicoUniversità degli Studi di Milano, I.R.C.C.S. Foundation, Cà Granda Ospedale Maggiore PoliclinicoBackground: Tinea corporis is a common mycotic infection in children. Staphylococcus aureus superinfections may be observed in atopic children with tinea corporis suffering from severe pruritus and consequent scratching. Objective: From 2006 to 2011, we observed 288 children with mycologically proven tinea corporis. In 39 of them (13.5%) tinea corporis was superinfected by S. aureus: all these children were affected by atopic dermatitis. We interpreted these bacterial superinfections as the clinical result of scratching due to pruritus. Methods: In 2012, we decided to treat all children with a single lesion of tinea corporis with a combination of 1% isoconazole nitrate and 0.1% diflucortolone valerate cream (one application/day for 5–7 days), followed by a treatment with isoconazole or clotrimazole or ciclopirox cream (two applications/day for two weeks). Results: From 2012 to 2014, we observed 108 children with tinea corporis confirmed by mycological examinations. Clinical and mycological recovery was observed in 93 of them (86.1%). Only four of these children (3.7%) developed S. aureus superinfections. Conclusions: Our study in atopic children with tinea corporis superinfected by S. aureus confirms that a topical therapy with the association isoconazole–diflucortolone is useful and safe.http://dx.doi.org/10.1080/09546634.2017.1360988atopic dermatitischildrendiflucortolone valerateisoconazole nitratestaphylococcus aureustinea corporis |
| spellingShingle | Stefano Veraldi Rossana Schianchi Paolo Pontini Alberto Gorani The association of isoconazole–diflucortolone in the treatment of pediatric tinea corporis Journal of Dermatological Treatment atopic dermatitis children diflucortolone valerate isoconazole nitrate staphylococcus aureus tinea corporis |
| title | The association of isoconazole–diflucortolone in the treatment of pediatric tinea corporis |
| title_full | The association of isoconazole–diflucortolone in the treatment of pediatric tinea corporis |
| title_fullStr | The association of isoconazole–diflucortolone in the treatment of pediatric tinea corporis |
| title_full_unstemmed | The association of isoconazole–diflucortolone in the treatment of pediatric tinea corporis |
| title_short | The association of isoconazole–diflucortolone in the treatment of pediatric tinea corporis |
| title_sort | association of isoconazole diflucortolone in the treatment of pediatric tinea corporis |
| topic | atopic dermatitis children diflucortolone valerate isoconazole nitrate staphylococcus aureus tinea corporis |
| url | http://dx.doi.org/10.1080/09546634.2017.1360988 |
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