The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
Introduction The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD). Material and methods FA levels of phospholipids fraction in serum and colon-biopsy specimen were measured in 17 patients with IBD...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2022-06-01
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| Series: | Archives of Medical Science |
| Subjects: | |
| Online Access: | https://www.archivesofmedicalscience.com/The-risk-of-essential-fatty-acid-insufficiency-in-patients-with-inflammatory-bowel,150041,0,2.html |
| Summary: | Introduction
The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD).
Material and methods
FA levels of phospholipids fraction in serum and colon-biopsy specimen were measured in 17 patients with IBD.
Results
A negative correlation between the histological activity of inflammation of the disease and the ratio of polyunsaturated FAs/no polyunsaturated FAs was observed. Moreover, the level of that ratio was lower in patients with IBDs as compared to control.
Conclusions
The FA profile in serum and in colon-biopsy specimen in patients with IBD is characteristic for essential fatty acid insufficiency. |
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| ISSN: | 1734-1922 1896-9151 |