The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen
Introduction The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD). Material and methods FA levels of phospholipids fraction in serum and colon-biopsy specimen were measured in 17 patients with IBD...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2022-06-01
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| Series: | Archives of Medical Science |
| Subjects: | |
| Online Access: | https://www.archivesofmedicalscience.com/The-risk-of-essential-fatty-acid-insufficiency-in-patients-with-inflammatory-bowel,150041,0,2.html |
| _version_ | 1797435308656033792 |
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| author | Jolanta Bugajska Joanna Berska Małgorzata Zwolińska-Wcisło Krystyna Sztefko |
| author_facet | Jolanta Bugajska Joanna Berska Małgorzata Zwolińska-Wcisło Krystyna Sztefko |
| author_sort | Jolanta Bugajska |
| collection | DOAJ |
| description | Introduction
The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD).
Material and methods
FA levels of phospholipids fraction in serum and colon-biopsy specimen were measured in 17 patients with IBD.
Results
A negative correlation between the histological activity of inflammation of the disease and the ratio of polyunsaturated FAs/no polyunsaturated FAs was observed. Moreover, the level of that ratio was lower in patients with IBDs as compared to control.
Conclusions
The FA profile in serum and in colon-biopsy specimen in patients with IBD is characteristic for essential fatty acid insufficiency. |
| first_indexed | 2024-03-09T10:46:17Z |
| format | Article |
| id | doaj.art-43536166c1f645dda4adf8b62c32c084 |
| institution | Directory Open Access Journal |
| issn | 1734-1922 1896-9151 |
| language | English |
| last_indexed | 2024-03-09T10:46:17Z |
| publishDate | 2022-06-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj.art-43536166c1f645dda4adf8b62c32c0842023-12-01T10:02:33ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512022-06-011841103110710.5114/aoms/150041150041The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimenJolanta Bugajska0Joanna Berska1Małgorzata Zwolińska-Wcisło2Krystyna Sztefko3Department of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, PolandDepartment of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, PolandDepartment of Food Chemistry and Nutrition, Jagiellonian University Medical College, Krakow, PolandDepartment of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, PolandIntroduction The aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD). Material and methods FA levels of phospholipids fraction in serum and colon-biopsy specimen were measured in 17 patients with IBD. Results A negative correlation between the histological activity of inflammation of the disease and the ratio of polyunsaturated FAs/no polyunsaturated FAs was observed. Moreover, the level of that ratio was lower in patients with IBDs as compared to control. Conclusions The FA profile in serum and in colon-biopsy specimen in patients with IBD is characteristic for essential fatty acid insufficiency.https://www.archivesofmedicalscience.com/The-risk-of-essential-fatty-acid-insufficiency-in-patients-with-inflammatory-bowel,150041,0,2.htmlfatty acidsinflammatory bowel diseaseessential fatty acid insufficiencyserumcolon biopsy specimen |
| spellingShingle | Jolanta Bugajska Joanna Berska Małgorzata Zwolińska-Wcisło Krystyna Sztefko The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen Archives of Medical Science fatty acids inflammatory bowel disease essential fatty acid insufficiency serum colon biopsy specimen |
| title | The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen |
| title_full | The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen |
| title_fullStr | The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen |
| title_full_unstemmed | The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen |
| title_short | The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen |
| title_sort | risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases fatty acid profile of phospholipids in serum and in colon biopsy specimen |
| topic | fatty acids inflammatory bowel disease essential fatty acid insufficiency serum colon biopsy specimen |
| url | https://www.archivesofmedicalscience.com/The-risk-of-essential-fatty-acid-insufficiency-in-patients-with-inflammatory-bowel,150041,0,2.html |
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