Ultrasound-guided percutaneous cholecystostomy as bridging or definitive treatment in patients with acute cholecystitis grade II or III

Background: We aimed to investigate the extent to which ultrasound (US)-guided percutaneous cholecystostomy (PC) is used as a bridging or definitive therapy for grade II and III acute cholecystitis and whether this treatment causes significant changes in C-reactive protein (CRP) and direct bilirubin...

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Main Authors: Çağrı Kesim, Özgür Özen
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023028086
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author Çağrı Kesim
Özgür Özen
author_facet Çağrı Kesim
Özgür Özen
author_sort Çağrı Kesim
collection DOAJ
description Background: We aimed to investigate the extent to which ultrasound (US)-guided percutaneous cholecystostomy (PC) is used as a bridging or definitive therapy for grade II and III acute cholecystitis and whether this treatment causes significant changes in C-reactive protein (CRP) and direct bilirubin (DB) levels in the first 72 h and the first three weeks. Methods: We included 145 consecutive patients who underwent PC over 17 years. No patient had cirrhosis. PC was performed in the interventional radiology department under US guidance. Results: US-guided PC was the definitive treatment for more than half of the patients (51.7%) and decreased DB levels significantly more than CRP levels. Conclusion: No statistically significant correlation between those whose CRP and DB levels normalized within three weeks and those who did not and required a second invasive procedure. Nevertheless, the bridging treatment group was significantly older than the definitive treatment group.
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spelling doaj.art-4355eada529a46b6a7833ddc65fe59562023-05-31T04:44:54ZengElsevierHeliyon2405-84402023-05-0195e15601Ultrasound-guided percutaneous cholecystostomy as bridging or definitive treatment in patients with acute cholecystitis grade II or IIIÇağrı Kesim0Özgür Özen1Başkent University, Konya Hospital, Department of Radiology, Interventional Radiology Section, Turkey; Corresponding author.Başkent University, Ankara Hospital, Department of Radiology, Interventional Radiology Section, TurkeyBackground: We aimed to investigate the extent to which ultrasound (US)-guided percutaneous cholecystostomy (PC) is used as a bridging or definitive therapy for grade II and III acute cholecystitis and whether this treatment causes significant changes in C-reactive protein (CRP) and direct bilirubin (DB) levels in the first 72 h and the first three weeks. Methods: We included 145 consecutive patients who underwent PC over 17 years. No patient had cirrhosis. PC was performed in the interventional radiology department under US guidance. Results: US-guided PC was the definitive treatment for more than half of the patients (51.7%) and decreased DB levels significantly more than CRP levels. Conclusion: No statistically significant correlation between those whose CRP and DB levels normalized within three weeks and those who did not and required a second invasive procedure. Nevertheless, the bridging treatment group was significantly older than the definitive treatment group.http://www.sciencedirect.com/science/article/pii/S2405844023028086Acute cholecystitisC-reactive proteinDirect bilirubinGallbladder drainagePercutaneous cholecystostomyUltrasound-guided procedure
spellingShingle Çağrı Kesim
Özgür Özen
Ultrasound-guided percutaneous cholecystostomy as bridging or definitive treatment in patients with acute cholecystitis grade II or III
Heliyon
Acute cholecystitis
C-reactive protein
Direct bilirubin
Gallbladder drainage
Percutaneous cholecystostomy
Ultrasound-guided procedure
title Ultrasound-guided percutaneous cholecystostomy as bridging or definitive treatment in patients with acute cholecystitis grade II or III
title_full Ultrasound-guided percutaneous cholecystostomy as bridging or definitive treatment in patients with acute cholecystitis grade II or III
title_fullStr Ultrasound-guided percutaneous cholecystostomy as bridging or definitive treatment in patients with acute cholecystitis grade II or III
title_full_unstemmed Ultrasound-guided percutaneous cholecystostomy as bridging or definitive treatment in patients with acute cholecystitis grade II or III
title_short Ultrasound-guided percutaneous cholecystostomy as bridging or definitive treatment in patients with acute cholecystitis grade II or III
title_sort ultrasound guided percutaneous cholecystostomy as bridging or definitive treatment in patients with acute cholecystitis grade ii or iii
topic Acute cholecystitis
C-reactive protein
Direct bilirubin
Gallbladder drainage
Percutaneous cholecystostomy
Ultrasound-guided procedure
url http://www.sciencedirect.com/science/article/pii/S2405844023028086
work_keys_str_mv AT cagrıkesim ultrasoundguidedpercutaneouscholecystostomyasbridgingordefinitivetreatmentinpatientswithacutecholecystitisgradeiioriii
AT ozgurozen ultrasoundguidedpercutaneouscholecystostomyasbridgingordefinitivetreatmentinpatientswithacutecholecystitisgradeiioriii