TERTmonitor—qPCR Detection of <i>TERTp</i> Mutations in Glioma

Telomerase promoter (TERTp) mutations are frequently observed in various types of tumours and commonly characterised by two specific hotspots located at positions −124 and −146 upstream of the start codon. They enhance <i>TERTp</i> activity, resulting in increased TERT expression. In cen...

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Bibliographic Details
Main Authors: João Paulo Brás, Tito Teles Jesus, Hugo Prazeres, Jorge Lima, Paula Soares, João Vinagre
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/9/1693