Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine bot...
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Format: | Article |
Language: | English |
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Korean Spine Society
2019-06-01
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Series: | Asian Spine Journal |
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Online Access: | http://www.asianspinejournal.org/upload/pdf/asj-2018-0096.pdf |
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author | Sina Rashidi Kikanloo Sandip Parshottam Tarpada Woojin Cho |
author_facet | Sina Rashidi Kikanloo Sandip Parshottam Tarpada Woojin Cho |
author_sort | Sina Rashidi Kikanloo |
collection | DOAJ |
description | Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS. |
first_indexed | 2024-12-18T19:41:21Z |
format | Article |
id | doaj.art-43591f17f63640f786da9416acf548b5 |
institution | Directory Open Access Journal |
issn | 1976-1902 1976-7846 |
language | English |
last_indexed | 2024-12-18T19:41:21Z |
publishDate | 2019-06-01 |
publisher | Korean Spine Society |
record_format | Article |
series | Asian Spine Journal |
spelling | doaj.art-43591f17f63640f786da9416acf548b52022-12-21T20:55:25ZengKorean Spine SocietyAsian Spine Journal1976-19021976-78462019-06-0113351952610.31616/asj.2018.00961042Etiology of Adolescent Idiopathic Scoliosis: A Literature ReviewSina Rashidi Kikanloo0Sandip Parshottam Tarpada1Woojin Cho Department of Orthopedic Surgery, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA Department of Orthopedic Surgery, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USAAdolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.http://www.asianspinejournal.org/upload/pdf/asj-2018-0096.pdfAdolescentScoliosisAdolescent idiopathic scoliosisEtiologyCobb angleReview |
spellingShingle | Sina Rashidi Kikanloo Sandip Parshottam Tarpada Woojin Cho Etiology of Adolescent Idiopathic Scoliosis: A Literature Review Asian Spine Journal Adolescent Scoliosis Adolescent idiopathic scoliosis Etiology Cobb angle Review |
title | Etiology of Adolescent Idiopathic Scoliosis: A Literature Review |
title_full | Etiology of Adolescent Idiopathic Scoliosis: A Literature Review |
title_fullStr | Etiology of Adolescent Idiopathic Scoliosis: A Literature Review |
title_full_unstemmed | Etiology of Adolescent Idiopathic Scoliosis: A Literature Review |
title_short | Etiology of Adolescent Idiopathic Scoliosis: A Literature Review |
title_sort | etiology of adolescent idiopathic scoliosis a literature review |
topic | Adolescent Scoliosis Adolescent idiopathic scoliosis Etiology Cobb angle Review |
url | http://www.asianspinejournal.org/upload/pdf/asj-2018-0096.pdf |
work_keys_str_mv | AT sinarashidikikanloo etiologyofadolescentidiopathicscoliosisaliteraturereview AT sandipparshottamtarpada etiologyofadolescentidiopathicscoliosisaliteraturereview AT woojincho etiologyofadolescentidiopathicscoliosisaliteraturereview |