Etiology of Adolescent Idiopathic Scoliosis: A Literature Review

Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine bot...

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Main Authors: Sina Rashidi Kikanloo, Sandip Parshottam Tarpada, Woojin Cho
Format: Article
Language:English
Published: Korean Spine Society 2019-06-01
Series:Asian Spine Journal
Subjects:
Online Access:http://www.asianspinejournal.org/upload/pdf/asj-2018-0096.pdf
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author Sina Rashidi Kikanloo
Sandip Parshottam Tarpada
Woojin Cho
author_facet Sina Rashidi Kikanloo
Sandip Parshottam Tarpada
Woojin Cho
author_sort Sina Rashidi Kikanloo
collection DOAJ
description Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.
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1976-7846
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spelling doaj.art-43591f17f63640f786da9416acf548b52022-12-21T20:55:25ZengKorean Spine SocietyAsian Spine Journal1976-19021976-78462019-06-0113351952610.31616/asj.2018.00961042Etiology of Adolescent Idiopathic Scoliosis: A Literature ReviewSina Rashidi Kikanloo0Sandip Parshottam Tarpada1Woojin Cho Department of Orthopedic Surgery, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA Department of Orthopedic Surgery, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USAAdolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.http://www.asianspinejournal.org/upload/pdf/asj-2018-0096.pdfAdolescentScoliosisAdolescent idiopathic scoliosisEtiologyCobb angleReview
spellingShingle Sina Rashidi Kikanloo
Sandip Parshottam Tarpada
Woojin Cho
Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
Asian Spine Journal
Adolescent
Scoliosis
Adolescent idiopathic scoliosis
Etiology
Cobb angle
Review
title Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_full Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_fullStr Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_full_unstemmed Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_short Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_sort etiology of adolescent idiopathic scoliosis a literature review
topic Adolescent
Scoliosis
Adolescent idiopathic scoliosis
Etiology
Cobb angle
Review
url http://www.asianspinejournal.org/upload/pdf/asj-2018-0096.pdf
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AT sandipparshottamtarpada etiologyofadolescentidiopathicscoliosisaliteraturereview
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