Dynamic regulation of cerebral blood flow and it's clinical, and laboratory markers in elderly patients with arterial hypertension

Aim: to estimate the dynamic regulation of cerebral blood flow (CBF) and significance of clinical, and laboratory parameters as a possible markers of CBF violations. Material. 179 elderly patients with arterial hypertension were involved in the study. Transcranial Doppler ultrasonography (Philips En...

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Main Authors: Tikhonova L.A., Sadjaya L.A., Malinova L.I.
Format: Article
Language:Russian
Published: Saratov State Medical University 2011-12-01
Series:Саратовский научно-медицинский журнал
Subjects:
Online Access:http://www.ssmj.ru/system/files/201104_842-845.pdf
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author Tikhonova L.A.
Sadjaya L.A.
Malinova L.I.
author_facet Tikhonova L.A.
Sadjaya L.A.
Malinova L.I.
author_sort Tikhonova L.A.
collection DOAJ
description Aim: to estimate the dynamic regulation of cerebral blood flow (CBF) and significance of clinical, and laboratory parameters as a possible markers of CBF violations. Material. 179 elderly patients with arterial hypertension were involved in the study. Transcranial Doppler ultrasonography (Philips Envisor HD, USA) was used for CBF parameters dynamics during orthostatic hypotension. Results. Main directions of CBF parameters changings (Friedman ANOVA p 0,0091 ... 0,012, coeff. of concordance 0,308 ... 0,691) were detected. Gender differences of CBF parameters, as well as blood pressure level influence upon CBF regulation during orthostatic hypertension were studied. Conclusion. Received data allow us to consider gender, controlled or uncontrolled hypertension, cytomorphological parameters of peripheral blood, diuretics usage as clinical, and laboratory markers of dynamic regulation of CBF in elderly patients with arterial hypertension
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spelling doaj.art-43598e82c91c44b9b6d4ddb1a549dedd2022-12-21T20:13:31ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал1995-00392076-25182011-12-0174842845Dynamic regulation of cerebral blood flow and it's clinical, and laboratory markers in elderly patients with arterial hypertensionTikhonova L.A.Sadjaya L.A.Malinova L.I.Aim: to estimate the dynamic regulation of cerebral blood flow (CBF) and significance of clinical, and laboratory parameters as a possible markers of CBF violations. Material. 179 elderly patients with arterial hypertension were involved in the study. Transcranial Doppler ultrasonography (Philips Envisor HD, USA) was used for CBF parameters dynamics during orthostatic hypotension. Results. Main directions of CBF parameters changings (Friedman ANOVA p 0,0091 ... 0,012, coeff. of concordance 0,308 ... 0,691) were detected. Gender differences of CBF parameters, as well as blood pressure level influence upon CBF regulation during orthostatic hypertension were studied. Conclusion. Received data allow us to consider gender, controlled or uncontrolled hypertension, cytomorphological parameters of peripheral blood, diuretics usage as clinical, and laboratory markers of dynamic regulation of CBF in elderly patients with arterial hypertensionhttp://www.ssmj.ru/system/files/201104_842-845.pdfageingarterial hypertensionintima-media complex thicknessvascular remodeling
spellingShingle Tikhonova L.A.
Sadjaya L.A.
Malinova L.I.
Dynamic regulation of cerebral blood flow and it's clinical, and laboratory markers in elderly patients with arterial hypertension
Саратовский научно-медицинский журнал
ageing
arterial hypertension
intima-media complex thickness
vascular remodeling
title Dynamic regulation of cerebral blood flow and it's clinical, and laboratory markers in elderly patients with arterial hypertension
title_full Dynamic regulation of cerebral blood flow and it's clinical, and laboratory markers in elderly patients with arterial hypertension
title_fullStr Dynamic regulation of cerebral blood flow and it's clinical, and laboratory markers in elderly patients with arterial hypertension
title_full_unstemmed Dynamic regulation of cerebral blood flow and it's clinical, and laboratory markers in elderly patients with arterial hypertension
title_short Dynamic regulation of cerebral blood flow and it's clinical, and laboratory markers in elderly patients with arterial hypertension
title_sort dynamic regulation of cerebral blood flow and it 039 s clinical and laboratory markers in elderly patients with arterial hypertension
topic ageing
arterial hypertension
intima-media complex thickness
vascular remodeling
url http://www.ssmj.ru/system/files/201104_842-845.pdf
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AT sadjayala dynamicregulationofcerebralbloodflowandit039sclinicalandlaboratorymarkersinelderlypatientswitharterialhypertension
AT malinovali dynamicregulationofcerebralbloodflowandit039sclinicalandlaboratorymarkersinelderlypatientswitharterialhypertension