Cortical astrocytes develop in a plastic manner at both clonal and cellular levels
Previous studies on astrocyte development have led to controversial results due to a lack of pertinent tools. Here, authors analyze large numbers of astrocyte clones generated by nearby cortical progenitors using the MAGIC Markers strategy and ChroMS 3D imaging, and show that clonally-related astroc...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2019-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-12791-5 |
| _version_ | 1818682395176468480 |
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| author | Solène Clavreul Lamiae Abdeladim Edwin Hernández-Garzón Dragos Niculescu Jason Durand Sio-Hoï Ieng Raphaëlle Barry Gilles Bonvento Emmanuel Beaurepaire Jean Livet Karine Loulier |
| author_facet | Solène Clavreul Lamiae Abdeladim Edwin Hernández-Garzón Dragos Niculescu Jason Durand Sio-Hoï Ieng Raphaëlle Barry Gilles Bonvento Emmanuel Beaurepaire Jean Livet Karine Loulier |
| author_sort | Solène Clavreul |
| collection | DOAJ |
| description | Previous studies on astrocyte development have led to controversial results due to a lack of pertinent tools. Here, authors analyze large numbers of astrocyte clones generated by nearby cortical progenitors using the MAGIC Markers strategy and ChroMS 3D imaging, and show that clonally-related astrocytes organize in a non-stereotyped manner and that cortical astrocyte subtypes are not intrinsically specified. |
| first_indexed | 2024-12-17T10:18:09Z |
| format | Article |
| id | doaj.art-435d94e6bca044b89496f3445b4f4c83 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T10:18:09Z |
| publishDate | 2019-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-435d94e6bca044b89496f3445b4f4c832022-12-21T21:52:52ZengNature PortfolioNature Communications2041-17232019-10-0110111410.1038/s41467-019-12791-5Cortical astrocytes develop in a plastic manner at both clonal and cellular levelsSolène Clavreul0Lamiae Abdeladim1Edwin Hernández-Garzón2Dragos Niculescu3Jason Durand4Sio-Hoï Ieng5Raphaëlle Barry6Gilles Bonvento7Emmanuel Beaurepaire8Jean Livet9Karine Loulier10Sorbonne Université, INSERM, CNRS, Institut de la VisionLaboratory for Optics and Biosciences, Ecole polytechnique, CNRS, INSERM, IP ParisCommissariat à l’Energie Atomique et aux Energies Alternatives (CEA), Département de la Recherche Fondamentale, Institut de biologie François Jacob, Molecular Imaging Research Center (MIRCen), CNRS UMR 9199, Université Paris-Sud, Université Paris-SaclaySorbonne Université, INSERM, CNRS, Institut de la VisionSorbonne Université, INSERM, CNRS, Institut de la VisionSorbonne Université, INSERM, CNRS, Institut de la VisionSorbonne Université, INSERM, CNRS, Institut de la VisionCommissariat à l’Energie Atomique et aux Energies Alternatives (CEA), Département de la Recherche Fondamentale, Institut de biologie François Jacob, Molecular Imaging Research Center (MIRCen), CNRS UMR 9199, Université Paris-Sud, Université Paris-SaclayLaboratory for Optics and Biosciences, Ecole polytechnique, CNRS, INSERM, IP ParisSorbonne Université, INSERM, CNRS, Institut de la VisionSorbonne Université, INSERM, CNRS, Institut de la VisionPrevious studies on astrocyte development have led to controversial results due to a lack of pertinent tools. Here, authors analyze large numbers of astrocyte clones generated by nearby cortical progenitors using the MAGIC Markers strategy and ChroMS 3D imaging, and show that clonally-related astrocytes organize in a non-stereotyped manner and that cortical astrocyte subtypes are not intrinsically specified.https://doi.org/10.1038/s41467-019-12791-5 |
| spellingShingle | Solène Clavreul Lamiae Abdeladim Edwin Hernández-Garzón Dragos Niculescu Jason Durand Sio-Hoï Ieng Raphaëlle Barry Gilles Bonvento Emmanuel Beaurepaire Jean Livet Karine Loulier Cortical astrocytes develop in a plastic manner at both clonal and cellular levels Nature Communications |
| title | Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
| title_full | Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
| title_fullStr | Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
| title_full_unstemmed | Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
| title_short | Cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
| title_sort | cortical astrocytes develop in a plastic manner at both clonal and cellular levels |
| url | https://doi.org/10.1038/s41467-019-12791-5 |
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