Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum.

Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum.

Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we generated 16.7 billion nucleotides of short read, shotgun sequences of cDNA from post-mortem cerebellar co...

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Bibliographic Details
Main Authors: Joann Mudge, Neil A Miller, Irina Khrebtukova, Ingrid E Lindquist, Gregory D May, Jim J Huntley, Shujun Luo, Lu Zhang, Jennifer C van Velkinburgh, Andrew D Farmer, Sharon Lewis, William D Beavis, Faye D Schilkey, Selene M Virk, C Forrest Black, M Kathy Myers, Lar C Mader, Ray J Langley, John P Utsey, Ryan W Kim, Rosalinda C Roberts, Sat Kirpal Khalsa, Meredith Garcia, Victoria Ambriz-Griffith, Richard Harlan, Wendy Czika, Stanton Martin, Russell D Wolfinger, Nora I Perrone-Bizzozero, Gary P Schroth, Stephen F Kingsmore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2576459?pdf=render

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