Single- and Two-Electron Reduction of Nitroaromatic Compounds by Flavoenzymes: Mechanisms and Implications for Cytotoxicity

Single- and Two-Electron Reduction of Nitroaromatic Compounds by Flavoenzymes: Mechanisms and Implications for Cytotoxicity

Nitroaromatic compounds (ArNO<sub>2</sub>) maintain their importance in relation to industrial processes, environmental pollution, and pharmaceutical application. The manifestation of toxicity/therapeutic action of nitroaromatics may involve their single- or two-electron reduction perfor...

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Bibliographic Details
Main Authors: Narimantas Čėnas, Aušra Nemeikaitė-Čėnienė, Lidija Kosychova
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
nitroaromatic compounds
flavoenzymes
cytotoxicity
oxidative stress
bioreductive activation
Online Access:https://www.mdpi.com/1422-0067/22/16/8534

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