Cortical glutamate and GABA are related to compulsive behaviour in individuals with obsessive compulsive disorder and healthy controls

Cortical glutamate and GABA are related to compulsive behaviour in individuals with obsessive compulsive disorder and healthy controls

Abstract There has been little analysis of neurochemical correlates of compulsive behaviour to illuminate its underlying neural mechanisms. We use 7-Tesla proton magnetic resonance spectroscopy (1H-MRS) to assess the balance of excitatory and inhibitory neurotransmission by measuring glutamate and G...

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Bibliographic Details
Main Authors: Marjan Biria, Paula Banca, Máiréad P. Healy, Engin Keser, Stephen J. Sawiak, Christopher T. Rodgers, Catarina Rua, Ana Maria Frota Lisbôa Pereira de Souza, Aleya A. Marzuki, Akeem Sule, Karen D. Ersche, Trevor W. Robbins
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38695-z

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