Evaluation of kidney allograft status using novel ultrasonic technologies

Early diagnosis of kidney allograft injury contributes to proper decisions regarding treatment strategy and promotes the long-term survival of both the recipients and the allografts. Although biopsy remains the gold standard, non-invasive methods of kidney allograft evaluation are required for clini...

Full description

Bibliographic Details
Main Authors: Cheng Yang, Mushuang Hu, Tongyu Zhu, Wanyuan He
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Asian Journal of Urology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221438821500079X
_version_ 1828408574634622976
author Cheng Yang
Mushuang Hu
Tongyu Zhu
Wanyuan He
author_facet Cheng Yang
Mushuang Hu
Tongyu Zhu
Wanyuan He
author_sort Cheng Yang
collection DOAJ
description Early diagnosis of kidney allograft injury contributes to proper decisions regarding treatment strategy and promotes the long-term survival of both the recipients and the allografts. Although biopsy remains the gold standard, non-invasive methods of kidney allograft evaluation are required for clinical practice. Recently, novel ultrasonic technologies have been applied in the evaluation and diagnosis of kidney allograft status, including tissue elasticity quantification using acoustic radiation force impulse (ARFI) and contrast-enhanced ultrasonography (CEUS). In this review, we discuss current opinions on the application of ARFI and CEUS for evaluating kidney allograft function and their possible influencing factors, advantages and limitations. We also compare these two technologies with other non-invasive diagnostic methods, including nuclear medicine and radiology. While the role of novel non-invasive ultrasonic technologies in the assessment of kidney allografts requires further investigation, the use of such technologies remains highly promising.
first_indexed 2024-12-10T11:41:46Z
format Article
id doaj.art-4363ebe1fa2b421e9f4e4a2a38d5e1d4
institution Directory Open Access Journal
issn 2214-3882
language English
last_indexed 2024-12-10T11:41:46Z
publishDate 2015-07-01
publisher Elsevier
record_format Article
series Asian Journal of Urology
spelling doaj.art-4363ebe1fa2b421e9f4e4a2a38d5e1d42022-12-22T01:50:13ZengElsevierAsian Journal of Urology2214-38822015-07-012314215010.1016/j.ajur.2015.06.008Evaluation of kidney allograft status using novel ultrasonic technologiesCheng Yang0Mushuang Hu1Tongyu Zhu2Wanyuan He3Department of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, Shanghai, ChinaDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, Shanghai, ChinaDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, Shanghai, ChinaDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai Institute of Imaging Medicine, Shanghai, ChinaEarly diagnosis of kidney allograft injury contributes to proper decisions regarding treatment strategy and promotes the long-term survival of both the recipients and the allografts. Although biopsy remains the gold standard, non-invasive methods of kidney allograft evaluation are required for clinical practice. Recently, novel ultrasonic technologies have been applied in the evaluation and diagnosis of kidney allograft status, including tissue elasticity quantification using acoustic radiation force impulse (ARFI) and contrast-enhanced ultrasonography (CEUS). In this review, we discuss current opinions on the application of ARFI and CEUS for evaluating kidney allograft function and their possible influencing factors, advantages and limitations. We also compare these two technologies with other non-invasive diagnostic methods, including nuclear medicine and radiology. While the role of novel non-invasive ultrasonic technologies in the assessment of kidney allografts requires further investigation, the use of such technologies remains highly promising.http://www.sciencedirect.com/science/article/pii/S221438821500079XUltrasoundAcoustic radiation force impulseContrast-enhanced ultrasonographyKidney transplantationNon-invasive
spellingShingle Cheng Yang
Mushuang Hu
Tongyu Zhu
Wanyuan He
Evaluation of kidney allograft status using novel ultrasonic technologies
Asian Journal of Urology
Ultrasound
Acoustic radiation force impulse
Contrast-enhanced ultrasonography
Kidney transplantation
Non-invasive
title Evaluation of kidney allograft status using novel ultrasonic technologies
title_full Evaluation of kidney allograft status using novel ultrasonic technologies
title_fullStr Evaluation of kidney allograft status using novel ultrasonic technologies
title_full_unstemmed Evaluation of kidney allograft status using novel ultrasonic technologies
title_short Evaluation of kidney allograft status using novel ultrasonic technologies
title_sort evaluation of kidney allograft status using novel ultrasonic technologies
topic Ultrasound
Acoustic radiation force impulse
Contrast-enhanced ultrasonography
Kidney transplantation
Non-invasive
url http://www.sciencedirect.com/science/article/pii/S221438821500079X
work_keys_str_mv AT chengyang evaluationofkidneyallograftstatususingnovelultrasonictechnologies
AT mushuanghu evaluationofkidneyallograftstatususingnovelultrasonictechnologies
AT tongyuzhu evaluationofkidneyallograftstatususingnovelultrasonictechnologies
AT wanyuanhe evaluationofkidneyallograftstatususingnovelultrasonictechnologies