Correlation between prostate volume and prostate-specific antigen in patients diagnosed with benign prostatic hyperplasia

Background: Prostate volume (PV) and serum prostate specific antigen (PSA) have been consistently linked to benign prostatic hyperplasia (BPH) disease progression especially when prostate volumes are >30mls and PSA>1.5ng/ml. PSA is produced by the ductal epithelial cells of the prostate. Unde...

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Main Authors: Udoh EA, Eyo AE, David DE
Format: Article
Language:English
Published: Nigerian Medical Association, Akwa Ibom State Branch 2020-12-01
Series:Ibom Medical Journal
Subjects:
Online Access:https://ibommedicaljournal.org/index.php/imjhome/article/view/199
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author Udoh EA
Eyo AE
David DE
author_facet Udoh EA
Eyo AE
David DE
author_sort Udoh EA
collection DOAJ
description Background: Prostate volume (PV) and serum prostate specific antigen (PSA) have been consistently linked to benign prostatic hyperplasia (BPH) disease progression especially when prostate volumes are >30mls and PSA>1.5ng/ml. PSA is produced by the ductal epithelial cells of the prostate. Understanding the natural history of prostate diseases requires knowledge of prostate volume and PSA. Objective: We set out to determine the correlation between prostate volume and PSA in our cohorts of men diagnosed with BPH. Methodology: Information from the case notes of 120 patients were retrieved including history, physical examination and result of relevant investigations. Data collated were analyzed using the statistical package for social sciences (SPSS) version 20.0 software. Results: Mean age of the patients was 64.95±9.22 years while mean PV and PSA were respectively 70.20±52.01mls and 4.58±3.32ng/ml. Correlation between PV and PSA was statistically significant: r= .407, P value was set at <.05. Conclusion: We concluded that PV and serum PSA levels have a direct relationship.
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spelling doaj.art-436539cb702143359605878bb34ba3d32024-03-06T12:03:47ZengNigerian Medical Association, Akwa Ibom State BranchIbom Medical Journal1597-71882735-99642020-12-0113310.61386/imj.v13i3.199Correlation between prostate volume and prostate-specific antigen in patients diagnosed with benign prostatic hyperplasiaUdoh EAEyo AEDavid DE Background: Prostate volume (PV) and serum prostate specific antigen (PSA) have been consistently linked to benign prostatic hyperplasia (BPH) disease progression especially when prostate volumes are >30mls and PSA>1.5ng/ml. PSA is produced by the ductal epithelial cells of the prostate. Understanding the natural history of prostate diseases requires knowledge of prostate volume and PSA. Objective: We set out to determine the correlation between prostate volume and PSA in our cohorts of men diagnosed with BPH. Methodology: Information from the case notes of 120 patients were retrieved including history, physical examination and result of relevant investigations. Data collated were analyzed using the statistical package for social sciences (SPSS) version 20.0 software. Results: Mean age of the patients was 64.95±9.22 years while mean PV and PSA were respectively 70.20±52.01mls and 4.58±3.32ng/ml. Correlation between PV and PSA was statistically significant: r= .407, P value was set at <.05. Conclusion: We concluded that PV and serum PSA levels have a direct relationship. https://ibommedicaljournal.org/index.php/imjhome/article/view/199Prostate VolumeSerum Prostate specific antigencorrelationBenign prostatic hyperplasia
spellingShingle Udoh EA
Eyo AE
David DE
Correlation between prostate volume and prostate-specific antigen in patients diagnosed with benign prostatic hyperplasia
Ibom Medical Journal
Prostate Volume
Serum Prostate specific antigen
correlation
Benign prostatic hyperplasia
title Correlation between prostate volume and prostate-specific antigen in patients diagnosed with benign prostatic hyperplasia
title_full Correlation between prostate volume and prostate-specific antigen in patients diagnosed with benign prostatic hyperplasia
title_fullStr Correlation between prostate volume and prostate-specific antigen in patients diagnosed with benign prostatic hyperplasia
title_full_unstemmed Correlation between prostate volume and prostate-specific antigen in patients diagnosed with benign prostatic hyperplasia
title_short Correlation between prostate volume and prostate-specific antigen in patients diagnosed with benign prostatic hyperplasia
title_sort correlation between prostate volume and prostate specific antigen in patients diagnosed with benign prostatic hyperplasia
topic Prostate Volume
Serum Prostate specific antigen
correlation
Benign prostatic hyperplasia
url https://ibommedicaljournal.org/index.php/imjhome/article/view/199
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