Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy
This work describes an improvement in the layout of coplanar electrodes for electrical impedance spectroscopy. We have developed, fabricated, and tested an improved electrode layout, which improves the sensitivity of an impedance flow cytometry chip. The improved chip was experimentally tested and c...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2014-12-01
|
| Series: | Micromachines |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2072-666X/6/1/110 |
| _version_ | 1819038091994726400 |
|---|---|
| author | Casper Hyttel Clausen Gustav Erik Skands Christian Vinther Bertelsen Winnie Edith Svendsen |
| author_facet | Casper Hyttel Clausen Gustav Erik Skands Christian Vinther Bertelsen Winnie Edith Svendsen |
| author_sort | Casper Hyttel Clausen |
| collection | DOAJ |
| description | This work describes an improvement in the layout of coplanar electrodes for electrical impedance spectroscopy. We have developed, fabricated, and tested an improved electrode layout, which improves the sensitivity of an impedance flow cytometry chip. The improved chip was experimentally tested and compared to a chip with a conventional electrode layout. The improved chip was able to discriminate 0.5 μm beads from 1 μm as opposed to the conventional chip. Furthermore, finite element modeling was used to simulate the improvements in electrical field density and uniformity between the electrodes of the new electrode layout. Good agreement was observed between the model and the obtained experimental results. |
| first_indexed | 2024-12-21T08:31:48Z |
| format | Article |
| id | doaj.art-4366e5a522884775a52374dd74f0f19c |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-12-21T08:31:48Z |
| publishDate | 2014-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-4366e5a522884775a52374dd74f0f19c2022-12-21T19:10:11ZengMDPI AGMicromachines2072-666X2014-12-016111012010.3390/mi6010110mi6010110Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance SpectroscopyCasper Hyttel Clausen0Gustav Erik Skands1Christian Vinther Bertelsen2Winnie Edith Svendsen3Department of Micro- and Nanotechnology, Technical University of Denmark, Oersteds Plads 345 East, DK 2800 Kgs. Lyngby, DenmarkSBT Aqua ApS, Diplomvej 381, 2800 Kgs. Lyngby, DenmarkDepartment of Micro- and Nanotechnology, Technical University of Denmark, Oersteds Plads 345 East, DK 2800 Kgs. Lyngby, DenmarkDepartment of Micro- and Nanotechnology, Technical University of Denmark, Oersteds Plads 345 East, DK 2800 Kgs. Lyngby, DenmarkThis work describes an improvement in the layout of coplanar electrodes for electrical impedance spectroscopy. We have developed, fabricated, and tested an improved electrode layout, which improves the sensitivity of an impedance flow cytometry chip. The improved chip was experimentally tested and compared to a chip with a conventional electrode layout. The improved chip was able to discriminate 0.5 μm beads from 1 μm as opposed to the conventional chip. Furthermore, finite element modeling was used to simulate the improvements in electrical field density and uniformity between the electrodes of the new electrode layout. Good agreement was observed between the model and the obtained experimental results.http://www.mdpi.com/2072-666X/6/1/110electrical impedance spectroscopysensitivityimproved designimpedance flow cytometry |
| spellingShingle | Casper Hyttel Clausen Gustav Erik Skands Christian Vinther Bertelsen Winnie Edith Svendsen Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy Micromachines electrical impedance spectroscopy sensitivity improved design impedance flow cytometry |
| title | Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy |
| title_full | Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy |
| title_fullStr | Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy |
| title_full_unstemmed | Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy |
| title_short | Coplanar Electrode Layout Optimized for Increased Sensitivity for Electrical Impedance Spectroscopy |
| title_sort | coplanar electrode layout optimized for increased sensitivity for electrical impedance spectroscopy |
| topic | electrical impedance spectroscopy sensitivity improved design impedance flow cytometry |
| url | http://www.mdpi.com/2072-666X/6/1/110 |
| work_keys_str_mv | AT casperhyttelclausen coplanarelectrodelayoutoptimizedforincreasedsensitivityforelectricalimpedancespectroscopy AT gustaverikskands coplanarelectrodelayoutoptimizedforincreasedsensitivityforelectricalimpedancespectroscopy AT christianvintherbertelsen coplanarelectrodelayoutoptimizedforincreasedsensitivityforelectricalimpedancespectroscopy AT winnieedithsvendsen coplanarelectrodelayoutoptimizedforincreasedsensitivityforelectricalimpedancespectroscopy |