Comparative effect of platelet- and mesenchymal stromal cell-derived extracellular vesicles on human cartilage explants using an ex vivo inflammatory osteoarthritis model

Comparative effect of platelet- and mesenchymal stromal cell-derived extracellular vesicles on human cartilage explants using an ex vivo inflammatory osteoarthritis model

Aims: Extracellular vesicles (EVs) are nanoparticles secreted by all cells, enriched in proteins, lipids, and nucleic acids related to cell-to-cell communication and vital components of cell-based therapies. Mesenchymal stromal cell (MSC)-derived EVs have been studied as an alternative for osteoart...

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Bibliographic Details
Main Authors: Maria A. Forteza-Genestra, Miquel Antich-Rosselló, Guillem Ramis-Munar, Javier Calvo, Antoni Gayà, Marta Monjo, Joana M. Ramis
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2023-10-01
Series:Bone & Joint Research
Subjects:
platelet lysate
osteoarthritis
extracellular vesicles
regenerative medicine
cartilage repair
human umbilical cord mesenchymal stromal cells
mesenchymal stromal cells
osteoarthritis (oa)
cartilage
platelets
glycosaminoglycans (gag)
collagens
mscs
dna
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.1210.BJR-2023-0109.R1

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