Surgeon-led 7-VINCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery Service
Antibiotic stewardship programs optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. In this prospective interventional study, a multidisciplinary team led by surgeons implemented a program aimed at shortening the duration of antibiotic treatment...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-12-01
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| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/10/1/11 |
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| author | Josep M. Badia Maria Batlle Montserrat Juvany Patricia Ruiz-de León Maria Sagalés M Angeles Pulido Gemma Molist Jordi Cuquet |
| author_facet | Josep M. Badia Maria Batlle Montserrat Juvany Patricia Ruiz-de León Maria Sagalés M Angeles Pulido Gemma Molist Jordi Cuquet |
| author_sort | Josep M. Badia |
| collection | DOAJ |
| description | Antibiotic stewardship programs optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. In this prospective interventional study, a multidisciplinary team led by surgeons implemented a program aimed at shortening the duration of antibiotic treatment <7 days. The impact of the intervention on antibiotic consumption adjusted to bed-days and discharges, and the isolation of multiresistant bacteria (MRB) was also studied. Furthermore, the surgeons were surveyed regarding their beliefs and feelings about the program. Out of 1409 patients, 40.7% received antibiotic therapy. Treatment continued for over 7 days in 21.5% of cases, and, as can be expected, source control was achieved in only 48.8% of these cases. The recommendations were followed in 90.2% of cases, the most frequent being to withdraw the treatment (55.6%). During the first 16 months of the intervention, a sharp decrease in the percentage of extended treatments, with R<sup>2</sup> = 0.111 was observed. The program was very well accepted by surgeons, and achieved a decrease in both the consumption of carbapenems and in the number of MRB isolations. Multidisciplinary stewardship teams led by surgeons seem to be well received and able to better manage antibiotic prescription in surgery. |
| first_indexed | 2024-03-10T13:47:18Z |
| format | Article |
| id | doaj.art-4377f3419a8646c2baeb7034ce514d0e |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-10T13:47:18Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-4377f3419a8646c2baeb7034ce514d0e2023-11-21T02:28:24ZengMDPI AGAntibiotics2079-63822020-12-011011110.3390/antibiotics10010011Surgeon-led 7-VINCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery ServiceJosep M. Badia0Maria Batlle1Montserrat Juvany2Patricia Ruiz-de León3Maria Sagalés4M Angeles Pulido5Gemma Molist6Jordi Cuquet7Department of Surgery, Hospital General Granollers, Universitat Internacional de Catalunya, 08402 Granollers, SpainDepartment of Surgery, Hospital General Granollers, Universitat Internacional de Catalunya, 08402 Granollers, SpainDepartment of Surgery, Hospital General Granollers, Universitat Internacional de Catalunya, 08402 Granollers, SpainDepartment of Surgery, Hospital General Granollers, Universitat Internacional de Catalunya, 08402 Granollers, SpainDepartment of Clinical Pharmacy, Hospital General Granollers, 08402 Granollers, SpainDepartment of Clinical Microbiology, Hospital General Granollers, 08402 Granollers, SpainDepartment of Statistics and Research, Hospital General Granollers, 08402 Granollers, SpainInfectious Diseases Unit, Hospital General Granollers, 08402 Granollers, SpainAntibiotic stewardship programs optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. In this prospective interventional study, a multidisciplinary team led by surgeons implemented a program aimed at shortening the duration of antibiotic treatment <7 days. The impact of the intervention on antibiotic consumption adjusted to bed-days and discharges, and the isolation of multiresistant bacteria (MRB) was also studied. Furthermore, the surgeons were surveyed regarding their beliefs and feelings about the program. Out of 1409 patients, 40.7% received antibiotic therapy. Treatment continued for over 7 days in 21.5% of cases, and, as can be expected, source control was achieved in only 48.8% of these cases. The recommendations were followed in 90.2% of cases, the most frequent being to withdraw the treatment (55.6%). During the first 16 months of the intervention, a sharp decrease in the percentage of extended treatments, with R<sup>2</sup> = 0.111 was observed. The program was very well accepted by surgeons, and achieved a decrease in both the consumption of carbapenems and in the number of MRB isolations. Multidisciplinary stewardship teams led by surgeons seem to be well received and able to better manage antibiotic prescription in surgery.https://www.mdpi.com/2079-6382/10/1/11anti-bacterial agents/therapeutic use*antimicrobial stewardship/organization and administration*antimicrobial stewardship/statistics and numerical data*drug resistancemultiplebacterial/drug effects |
| spellingShingle | Josep M. Badia Maria Batlle Montserrat Juvany Patricia Ruiz-de León Maria Sagalés M Angeles Pulido Gemma Molist Jordi Cuquet Surgeon-led 7-VINCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery Service Antibiotics anti-bacterial agents/therapeutic use* antimicrobial stewardship/organization and administration* antimicrobial stewardship/statistics and numerical data* drug resistance multiple bacterial/drug effects |
| title | Surgeon-led 7-VINCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery Service |
| title_full | Surgeon-led 7-VINCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery Service |
| title_fullStr | Surgeon-led 7-VINCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery Service |
| title_full_unstemmed | Surgeon-led 7-VINCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery Service |
| title_short | Surgeon-led 7-VINCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery Service |
| title_sort | surgeon led 7 vincut antibiotic stewardship intervention decreases duration of treatment and carbapenem use in a general surgery service |
| topic | anti-bacterial agents/therapeutic use* antimicrobial stewardship/organization and administration* antimicrobial stewardship/statistics and numerical data* drug resistance multiple bacterial/drug effects |
| url | https://www.mdpi.com/2079-6382/10/1/11 |
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