The oncogenic mechanisms of the Janus kinase-signal transducer and activator of transcription pathway in digestive tract tumors

The oncogenic mechanisms of the Janus kinase-signal transducer and activator of transcription pathway in digestive tract tumors

Abstract Digestive tract tumors are heterogeneous and involve the dysregulation of multiple signaling pathways. The Janus kinase-signal transducer and activator of transcription (JAK–STAT) pathway plays a notable role in the oncogenesis of digestive tract tumors. Typically activated by pro-inflammat...

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Bibliographic Details
Main Authors: Ruihong Zhao, Zhangmin Hu, Xiaoli Zhang, Shujuan Huang, Guodong Yu, Zhe Wu, Wei Yu, Juan Lu, Bing Ruan
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
JAK
STAT
Digestive tract tumors
Biological functions
Oncogenic mechanism
Online Access:https://doi.org/10.1186/s12964-023-01421-9

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