Is male infertility a forerunner to cancer?
PURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. RESULTS: Both of these disorders are associated with te...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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Sociedade Brasileira de Urologia
2010-10-01
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Series: | International Brazilian Journal of Urology |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000500002 |
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author | Whitney R. Burns Edmund Sabanegh Rima Dada Brandon Rein Ashok Agarwal |
author_facet | Whitney R. Burns Edmund Sabanegh Rima Dada Brandon Rein Ashok Agarwal |
author_sort | Whitney R. Burns |
collection | DOAJ |
description | PURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. RESULTS: Both of these disorders are associated with testicular dysgenesis syndrome and have also been traced to mutations in genes involving DNA repair and tumor suppression, as well as environmental exposure. CONCLUSION: The identification and examination of these common points of origin supports the integration of testicular cancer screenings into the routine evaluation of infertile men. |
first_indexed | 2024-12-12T03:33:12Z |
format | Article |
id | doaj.art-43796f403c1f4527a54c4bdfcc613305 |
institution | Directory Open Access Journal |
issn | 1677-5538 1677-6119 |
language | English |
last_indexed | 2024-12-12T03:33:12Z |
publishDate | 2010-10-01 |
publisher | Sociedade Brasileira de Urologia |
record_format | Article |
series | International Brazilian Journal of Urology |
spelling | doaj.art-43796f403c1f4527a54c4bdfcc6133052022-12-22T00:39:51ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-55381677-61192010-10-0136552753610.1590/S1677-55382010000500002Is male infertility a forerunner to cancer?Whitney R. BurnsEdmund SabaneghRima DadaBrandon ReinAshok AgarwalPURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. RESULTS: Both of these disorders are associated with testicular dysgenesis syndrome and have also been traced to mutations in genes involving DNA repair and tumor suppression, as well as environmental exposure. CONCLUSION: The identification and examination of these common points of origin supports the integration of testicular cancer screenings into the routine evaluation of infertile men.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000500002male infertilityendocrine-disruptiontesticular cancertesticular dysgenesis |
spellingShingle | Whitney R. Burns Edmund Sabanegh Rima Dada Brandon Rein Ashok Agarwal Is male infertility a forerunner to cancer? International Brazilian Journal of Urology male infertility endocrine-disruption testicular cancer testicular dysgenesis |
title | Is male infertility a forerunner to cancer? |
title_full | Is male infertility a forerunner to cancer? |
title_fullStr | Is male infertility a forerunner to cancer? |
title_full_unstemmed | Is male infertility a forerunner to cancer? |
title_short | Is male infertility a forerunner to cancer? |
title_sort | is male infertility a forerunner to cancer |
topic | male infertility endocrine-disruption testicular cancer testicular dysgenesis |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000500002 |
work_keys_str_mv | AT whitneyrburns ismaleinfertilityaforerunnertocancer AT edmundsabanegh ismaleinfertilityaforerunnertocancer AT rimadada ismaleinfertilityaforerunnertocancer AT brandonrein ismaleinfertilityaforerunnertocancer AT ashokagarwal ismaleinfertilityaforerunnertocancer |