Is male infertility a forerunner to cancer?

PURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. RESULTS: Both of these disorders are associated with te...

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Main Authors: Whitney R. Burns, Edmund Sabanegh, Rima Dada, Brandon Rein, Ashok Agarwal
Format: Article
Language:English
Published: Sociedade Brasileira de Urologia 2010-10-01
Series:International Brazilian Journal of Urology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000500002
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author Whitney R. Burns
Edmund Sabanegh
Rima Dada
Brandon Rein
Ashok Agarwal
author_facet Whitney R. Burns
Edmund Sabanegh
Rima Dada
Brandon Rein
Ashok Agarwal
author_sort Whitney R. Burns
collection DOAJ
description PURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. RESULTS: Both of these disorders are associated with testicular dysgenesis syndrome and have also been traced to mutations in genes involving DNA repair and tumor suppression, as well as environmental exposure. CONCLUSION: The identification and examination of these common points of origin supports the integration of testicular cancer screenings into the routine evaluation of infertile men.
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spelling doaj.art-43796f403c1f4527a54c4bdfcc6133052022-12-22T00:39:51ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-55381677-61192010-10-0136552753610.1590/S1677-55382010000500002Is male infertility a forerunner to cancer?Whitney R. BurnsEdmund SabaneghRima DadaBrandon ReinAshok AgarwalPURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links. RESULTS: Both of these disorders are associated with testicular dysgenesis syndrome and have also been traced to mutations in genes involving DNA repair and tumor suppression, as well as environmental exposure. CONCLUSION: The identification and examination of these common points of origin supports the integration of testicular cancer screenings into the routine evaluation of infertile men.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000500002male infertilityendocrine-disruptiontesticular cancertesticular dysgenesis
spellingShingle Whitney R. Burns
Edmund Sabanegh
Rima Dada
Brandon Rein
Ashok Agarwal
Is male infertility a forerunner to cancer?
International Brazilian Journal of Urology
male infertility
endocrine-disruption
testicular cancer
testicular dysgenesis
title Is male infertility a forerunner to cancer?
title_full Is male infertility a forerunner to cancer?
title_fullStr Is male infertility a forerunner to cancer?
title_full_unstemmed Is male infertility a forerunner to cancer?
title_short Is male infertility a forerunner to cancer?
title_sort is male infertility a forerunner to cancer
topic male infertility
endocrine-disruption
testicular cancer
testicular dysgenesis
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000500002
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AT rimadada ismaleinfertilityaforerunnertocancer
AT brandonrein ismaleinfertilityaforerunnertocancer
AT ashokagarwal ismaleinfertilityaforerunnertocancer