Type VI Secretion Systems Present New Insights on Pathogenic Yersinia
The type VI secretion system (T6SS) is a versatile secretion system widely distributed in Gram-negative bacteria that delivers multiple effector proteins into either prokaryotic or eukaryotic cells, or into the extracellular milieu. T6SS participates in various physiological processes including bact...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-07-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fcimb.2018.00260/full |
| _version_ | 1811294736629104640 |
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| author | Xiaobing Yang Xiaobing Yang Junfeng Pan Yao Wang Xihui Shen Xihui Shen |
| author_facet | Xiaobing Yang Xiaobing Yang Junfeng Pan Yao Wang Xihui Shen Xihui Shen |
| author_sort | Xiaobing Yang |
| collection | DOAJ |
| description | The type VI secretion system (T6SS) is a versatile secretion system widely distributed in Gram-negative bacteria that delivers multiple effector proteins into either prokaryotic or eukaryotic cells, or into the extracellular milieu. T6SS participates in various physiological processes including bacterial competition, host infection, and stress response. Three pathogenic Yersinia species, namely Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica, possess different copies of T6SSs with distinct biological functions. This review summarizes the pathogenic, antibacterial, and stress-resistant roles of T6SS in Yersinia and the ion-transporting ability in Y. pseudotuberculosis. In addition, the T6SS-related effectors and regulators identified in Yersinia are discussed. |
| first_indexed | 2024-04-13T05:21:53Z |
| format | Article |
| id | doaj.art-437bd6ff9a1f400a9de0ec1e15ba477c |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-04-13T05:21:53Z |
| publishDate | 2018-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-437bd6ff9a1f400a9de0ec1e15ba477c2022-12-22T03:00:43ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882018-07-01810.3389/fcimb.2018.00260391276Type VI Secretion Systems Present New Insights on Pathogenic YersiniaXiaobing Yang0Xiaobing Yang1Junfeng Pan2Yao Wang3Xihui Shen4Xihui Shen5State Key Laboratory of Crop Stress Biology for Arid Areas, College of Life Sciences, Northwest A&F University, Yangling, ChinaShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, ChinaShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, ChinaShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, ChinaState Key Laboratory of Crop Stress Biology for Arid Areas, College of Life Sciences, Northwest A&F University, Yangling, ChinaShaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, ChinaThe type VI secretion system (T6SS) is a versatile secretion system widely distributed in Gram-negative bacteria that delivers multiple effector proteins into either prokaryotic or eukaryotic cells, or into the extracellular milieu. T6SS participates in various physiological processes including bacterial competition, host infection, and stress response. Three pathogenic Yersinia species, namely Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica, possess different copies of T6SSs with distinct biological functions. This review summarizes the pathogenic, antibacterial, and stress-resistant roles of T6SS in Yersinia and the ion-transporting ability in Y. pseudotuberculosis. In addition, the T6SS-related effectors and regulators identified in Yersinia are discussed.https://www.frontiersin.org/article/10.3389/fcimb.2018.00260/fullpathogenic Yersiniatype VI secretion system (T6SS)functioneffectorsregulation |
| spellingShingle | Xiaobing Yang Xiaobing Yang Junfeng Pan Yao Wang Xihui Shen Xihui Shen Type VI Secretion Systems Present New Insights on Pathogenic Yersinia Frontiers in Cellular and Infection Microbiology pathogenic Yersinia type VI secretion system (T6SS) function effectors regulation |
| title | Type VI Secretion Systems Present New Insights on Pathogenic Yersinia |
| title_full | Type VI Secretion Systems Present New Insights on Pathogenic Yersinia |
| title_fullStr | Type VI Secretion Systems Present New Insights on Pathogenic Yersinia |
| title_full_unstemmed | Type VI Secretion Systems Present New Insights on Pathogenic Yersinia |
| title_short | Type VI Secretion Systems Present New Insights on Pathogenic Yersinia |
| title_sort | type vi secretion systems present new insights on pathogenic yersinia |
| topic | pathogenic Yersinia type VI secretion system (T6SS) function effectors regulation |
| url | https://www.frontiersin.org/article/10.3389/fcimb.2018.00260/full |
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