Lewis, Fischer 344, and Sprague-Dawley rats display differences in lipid peroxidation, motor recovery, and rubrospinal tract preservation after spinal cord injury.

Lewis, Fischer 344, and Sprague-Dawley rats display differences in lipid peroxidation, motor recovery, and rubrospinal tract preservation after spinal cord injury.

The rat is the most common animal model for the preclinical validation of neuroprotective therapies in spinal cord injury (SCI). Lipid peroxidation (LP) is a hallmark of the damage triggered after SCI. Free radicals react with fatty acids causing cellular and membrane disruption. LP accounts for a c...

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Bibliographic Details
Main Authors: Humberto eMestre, Manuel eRamirez, Elisa eGarcia, Susana eMartiñón, Yolanda eCruz, Maria G. Campos, Antonio eIbarra
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Neurology
Subjects:
Lipid Peroxidation
Fischer 344 rats
spinal cord injury
motor recovery
rubrospinal tract
Sprague-Dawley rat
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00108/full

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