A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx

A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx

The roles of bactericidal cathelicidins against bacterial infection have been extensively studied. However, the antibacterial property and mechanism of action of non-bactericidal cathelicidins are rarely known. Herein, a novel naturally occurring cathelicidin (PopuCATH) from tree frog (Polypedates p...

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Bibliographic Details
Main Authors: Yang Yang, Jing Wu, Qiao Li, Jing Wang, Lixian Mu, Li Hui, Min Li, Wei Xu, Hailong Yang, Lin Wei
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
antimicrobial peptide
cathelicidin
prophylaxis
phagocyte influx
tree frog
amphibian
Online Access:https://elifesciences.org/articles/72849

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