Silibinin Inhibits NSCLC Metastasis by Targeting the EGFR/LOX Pathway

Silibinin Inhibits NSCLC Metastasis by Targeting the EGFR/LOX Pathway

Tumor metastasis is the most lethal and debilitating process that threatens cancer patients. Among the regulators involved in tumor metastasis, lysyl oxidase (LOX) is an important contributor for tumor invasion, migration and the formation of the pre-metastatic niche. Although the relationship betwe...

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Bibliographic Details
Main Authors: Xiaoying Hou, Hongzhi Du, Xingping Quan, Lei Shi, Qianqian Zhang, Yao Wu, Yang Liu, Jing Xiao, Yong Li, Ligong Lu, Xun Ai, Meixiao Zhan, Shengtao Yuan, Li Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
lysyl oxidase
EGFR
silibinin
NSCLC
metastasis
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00021/full

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